Lucid Monkshood
Aconitum leucostomum
Aconitum leucostomum is a plant traditionally not used in any known medical practices. Scientific studies have shown that climate change promotes its distribution, with high suitability areas shifting southeast and to higher altitudes. While two new C18-diterpenoid alkaloids were identified from the plant, none demonstrated significant acetylcholinesterase inhibitory or neuroprotective effects. The crude drug, processed products, and monomer components of Aconitum leucostomum have been found to inhibit cell proliferation and enhance apoptosis in HFLS-RA cells, while DLTD (a component) inhibits dendritic cell maturation and inflammatory factor secretion, with these effects linked to miRNA regulation. No major safety issues or drug interactions have been recorded for Aconitum leucostomum.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that climate change promotes the distribution of Aconitum leucostomum, while human activities inhibit it, with high suitability areas shifting southeast and to higher altitudes in the future.
- Two new C18-diterpenoid alkaloids were identified from Aconitum leucostomum, but none showed significant acetylcholinesterase inhibitory or neuroprotective effects.
- Aconitum leucostomum crude drug, processed products, and monomer components inhibited cell proliferation and enhanced apoptosis in HFLS-RA cells.
- DLTD inhibits dendritic cell maturation and inflammatory factor secretion, with miR-511-3p potentially involved.
Frequently asked questions
What is Lucid Monkshood?
Lucid Monkshood (Aconitum leucostomum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lucid Monkshood?
4 sourced findings are recorded for Lucid Monkshood; the strongest carries evidence grade D. For example: The study found that climate change promotes the distribution of Aconitum leucostomum, while human activities inhibit it, with high suitability areas shifting southeast and to higher altitudes in the future.
How strong is the evidence for Lucid Monkshood?
The strongest finding for Lucid Monkshood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lucid Monkshood safe? What are the side effects?
No major safety issues are recorded for Lucid Monkshood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lucid Monkshood interact with medications?
No drug interactions are recorded for Lucid Monkshood in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Lucid Monkshood?
Lucid Monkshood is also known as: Борец белоустный.
Is Lucid Monkshood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Anti-rheumatic effects of Aconitum leucostomum Worosch. on human fibroblast-like synoviocyte rheumatoid arthritis cells. literature abstract metadata
- T2 Mechanism of miRNA-based Aconitum leucostomum Worosch. Monomer inhibition of bone marrow-derived dendritic cell maturation. literature abstract metadata
- T2 Two New C18 -Diterpenoid Alkaloids from Aconitum leucostomum Worosch. literature abstract metadata
- T2 Impacts of climate change and human activity on the potential distribution of Aconitum leucostomum in China. literature abstract metadata