Dzungaria Monkshood
Aconitum soongaricum
Aconitum soongaricum is a traditional medicinal plant, though specific uses within traditional practices have not been documented. Research indicates that processed products derived from this plant can inhibit ovarian cancer growth in vivo by modulating the PI3K/AKT signaling pathway and show promise in reducing inflammation associated with osteoarthritis through macrophage polarization and metabolic reprogramming. However, evidence is limited to laboratory studies, and clinical trials have not been conducted. Aconitine, a compound found in this plant, has been shown to induce neuronal apoptosis via mitochondrial calcium overload and energy metabolism disorder, highlighting potential neurotoxic effects. Songorine, another diterpenoid alkaloid from Aconitum soongaricum, exhibits anti-arrhythmic and anti-inflammatory properties but lacks clinical validation. No major safety concerns or recorded drug interactions have been identified to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Processed products of Aconitum soongaricum significantly inhibited ovarian cancer growth in vivo by regulating the PI3K/AKT signaling pathway.
- Songorine modulates macrophage polarization and metabolic reprogramming, reducing inflammation in osteoarthritis.
- Aconitine induced neuronal apoptosis through mitochondrial calcium overload due to up-regulated MCU expression, affecting ATP production and membrane potential.
- Songorine exhibits multiple biological activities including anti-arrhythmic, anti-inflammatory, and anxiolytic effects but has not been tested clinically.
Frequently asked questions
What is Dzungaria Monkshood?
Dzungaria Monkshood (Aconitum soongaricum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Dzungaria Monkshood?
4 sourced findings are recorded for Dzungaria Monkshood; the strongest carries evidence grade D. For example: Processed products of Aconitum soongaricum significantly inhibited ovarian cancer growth in vivo by regulating the PI3K/AKT signaling pathway.
How strong is the evidence for Dzungaria Monkshood?
The strongest finding for Dzungaria Monkshood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Dzungaria Monkshood safe? What are the side effects?
No major safety issues are recorded for Dzungaria Monkshood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Dzungaria Monkshood interact with medications?
No drug interactions are recorded for Dzungaria Monkshood in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Dzungaria Monkshood?
Dzungaria Monkshood is also known as: Борец джунгарский.
Is Dzungaria Monkshood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Therapeutic potential of songorine, a diterpenoid alkaloid of the genus Aconitum. literature abstract metadata
- T2 Mechanism of aconitine mediated neuronal apoptosis induced by mitochondrial calcium overload caused by MCU. literature abstract metadata
- T2 Songorine modulates macrophage polarization and metabolic reprogramming to alleviate inflammation in osteoarthritis. literature abstract metadata
- T2 Processed Products of Aconitum soongaricum Stapf. Inhibit the Growth of Ovarian Cancer Cells In vivo via Regulating the PI3K/AKT Signal Pathway. literature abstract metadata