Alangium
Alangium
Alangium is a genus of plants traditionally used in various Asian cultures for its purported medicinal properties, though specific uses are not well-documented. Scientific studies have shown that compounds isolated from Alangium species exhibit anti-proliferative and migration-inhibiting effects on certain cell lines, as well as significant antioxidant, antidiabetic, and hypolipidemic activities when tested in combination with other plants like Ocimum sanctum. Both Carapichea ipecacuanha and Alangium salviifolium are involved in the biosynthesis of ipecac alkaloids through a nonenzymatic Pictet-Spengler reaction, but they use different monoterpene precursors. The study also identified organ-specific bioactive metabolites in extracts from Alangium salviifolium that showed varying concentrations and cytotoxicity against A431 cells. To date, no major safety issues or drug interactions have been recorded for Alangium.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified organ-specific bioactive metabolites in Alangium salviifolium extracts, showing varying concentrations and cytotoxicity against A431 cells.
- The study found that Alangium salvifolium and Ocimum sanctum extracts, both individually and combined, showed significant antioxidant, antidiabetic, and hypolipidemic activities.
- Both Carapichea ipecacuanha and Alangium salviifolium initiate ipecac alkaloid biosynthesis through a nonenzymatic Pictet-Spengler reaction, though they use distinct monoterpene precursors.
- Mansonone E, isolated from Alangium platanifolium, showed notable anti-proliferative and migration-inhibiting effects on SW620 cells.
Frequently asked questions
What is Alangium?
Alangium (Alangium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Alangium?
4 sourced findings are recorded for Alangium; the strongest carries evidence grade D. For example: The study identified organ-specific bioactive metabolites in Alangium salviifolium extracts, showing varying concentrations and cytotoxicity against A431 cells.
How strong is the evidence for Alangium?
The strongest finding for Alangium carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Alangium safe? What are the side effects?
No major safety issues are recorded for Alangium in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Alangium interact with medications?
No drug interactions are recorded for Alangium in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Alangium?
Alangium is also known as: Алангиум.
Is Alangium a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Ipecac alkaloid biosynthesis in two evolutionarily distant plants. literature abstract metadata
- T2 Synergistic evaluation of anti-diabetic and hypolipidemic effects of Alangium salvifolium and Ocimum sanctum extracts. literature abstract metadata
- T2 Cadinane sesquiterpenes from Alangium platanifolium: structural elucidation and anti-colorectal cancer biological evaluation. literature abstract metadata
- T2 Multi-technique comparative analysis of bioactive metabolites in Alangium salviifolium (L.f.) Wangerin leaf, fruit and seed extracts using UV-Vis, FTIR, HPLC, LCMS and cytotoxicity evaluation on A431 cell line. literature abstract metadata