Levantnut
Anamirta cocculus
Anamirta cocculus, a plant traditionally used in Ayurvedic medicine, has not been extensively documented for specific traditional uses. Scientific evidence indicates that its ethyl acetate extract exhibits potent cytotoxicity against ovarian and colorectal cancer cells with minimal toxicity to normal cells, suggesting potential anti-cancer properties through mechanisms involving apoptosis induction. The study also identified characteristic compounds from Anamirta cocculus in the Vertigoheel formulation, which improved visual recognition memory and spatial working memory in rodents but did not fully address all scopolamine-induced impairments. Additionally, combining HPTLC and Bar-HRM methods can effectively differentiate Anamirta cocculus from related species such as Mallotus repandus and Croton caudatus. No major safety issues or recorded drug interactions have been identified for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The ethyl acetate extract of Anamirta cocculus showed potent cytotoxicity against ovarian and colorectal cancer cell lines with minimal toxicity to normal cells, inducing apoptosis through interactions with key proteins.
- The study identified characteristic compounds from each ingredient in Vertigoheel, including picrotoxinin and picrotin from Anamirta cocculus.
- VH-04 improved visual recognition memory and spatial working memory in rodents, but not all scopolamine-induced impairments.
- The study found that combining HPTLC and Bar-HRM methods could differentiate Mallotus repandus from Anamirta cocculus and Croton caudatus.
Frequently asked questions
What is Levantnut?
Levantnut (Anamirta cocculus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Levantnut?
4 sourced findings are recorded for Levantnut; the strongest carries evidence grade D. For example: The ethyl acetate extract of Anamirta cocculus showed potent cytotoxicity against ovarian and colorectal cancer cell lines with minimal toxicity to normal cells, inducing apoptosis through interactions with key proteins.
How strong is the evidence for Levantnut?
The strongest finding for Levantnut carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Levantnut safe? What are the side effects?
No major safety issues are recorded for Levantnut in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Levantnut interact with medications?
No drug interactions are recorded for Levantnut in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Levantnut?
Levantnut is also known as: Анамирта коккулюсовидная, coque du Levant.
Is Levantnut a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Combining DNA and HPTLC profiles to differentiate a pain relief herb, Mallotus repandus, from plants sharing the same common name, "Kho-Khlan". literature abstract metadata
- T2 Vertigoheel promotes rodent cognitive performance in multiple memory tests. literature abstract metadata
- T2 Unveiling the anticancer potential of Anamirta cocculus (L.) Wight& Arn.: Evidences from cytotoxicity studies, apoptosis analysis, and molecular docking. literature abstract metadata
- T2 Liquid Chromatography-Mass Spectrometry-Based Molecular Profiling of Vertigoheel. literature abstract metadata