Dahurian angelica

Angelica dahurica

Angelica dahurica, a traditional medicinal plant used primarily in East Asian medicine, particularly in China, has a long history of use for respiratory and digestive ailments. Scientific evidence suggests that its active compounds may have beneficial effects on liver function, muscle atrophy, allergic rhinitis, and cognitive function, though the strength of these findings varies. For instance, ADP (Angelica dahurica polysaccharide) has shown promise in reducing liver injury markers and improving antioxidant status in animal models. Additionally, extracts from Angelica dahurica have alleviated muscle atrophy associated with peripheral nerve injuries and may help reduce inflammation related to allergic rhinitis by restoring the nasal epithelial barrier integrity. Imperatorin, a compound found in ADP, has also been observed to partially restore memory and behavioral impairments caused by REM sleep deprivation, possibly through its effects on BDNF and CREB expression. Safety records for Angelica dahurica indicate no major issues have been recorded, but as with any herbal supplement, individual reactions may vary. There are currently no reported drug interactions associated with this plant, though further research is needed to fully understand its potential impacts in combination with other medications or treatments.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • Angelica dahurica polysaccharide alleviated hippocampal damage induced by ovariectomy/galactose in rats by enhancing antioxidant capacity and regulating glycerophospholipid metabolism. D PMID
  • ADP reduced liver injury markers and improved antioxidant status in ovariectomized/D-galactose rats. D PMID
  • The study found that imperatorin from Angelica dahurica alleviates allergic rhinitis symptoms by reducing inflammation and restoring nasal epithelial barrier integrity. D PMID
  • Angelica dahurica extract alleviated muscle atrophy in rats with peripheral nerve injury, largely independently of its analgesic effects. D PMID
  • Imperatorin partially restored memory and behavioral impairments induced by REM sleep deprivation in male rats, particularly affecting BDNF and CREB expression. D PMID

Frequently asked questions

What is Dahurian angelica?

Dahurian angelica (Angelica dahurica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Dahurian angelica?

5 sourced findings are recorded for Dahurian angelica; the strongest carries evidence grade D. For example: Angelica dahurica polysaccharide alleviated hippocampal damage induced by ovariectomy/galactose in rats by enhancing antioxidant capacity and regulating glycerophospholipid metabolism.

How strong is the evidence for Dahurian angelica?

The strongest finding for Dahurian angelica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Dahurian angelica safe? What are the side effects?

No major safety issues are recorded for Dahurian angelica in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Dahurian angelica interact with medications?

No drug interactions are recorded for Dahurian angelica in our sources. This does not rule them out — check with a pharmacist.

Is Dahurian angelica a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Protective effects of Angelica dahurica polysaccharide on oxidative stress and liver injury induced by ovariectomized/D-galactose in rats. literature abstract metadata
  2. T2 Imperatorin restores behavioral and recognition memory deficits induced by REM sleep deprivation in male rats. literature abstract metadata
  3. T2 Therapeutic mechanism of imperatorin in allergic rhinitis via anti-inflammatory action and restoration of nasal epithelial barrier integrity. literature abstract metadata
  4. T2 Angelica dahurica alleviates peripheral nerve injury-induced muscle atrophy via the Phlpp2-Akt-FoxO3α axis independently of analgesia. literature abstract metadata
  5. T2 Protective effects of Angelica dahurica polysaccharide on alleviating hippocampus injury induced by ovariectomized/D-galactose in rats by inhibiting oxidative stress and its serum metabolomics. literature abstract metadata