Kidney-vetches

Anthyllis

Anthyllis, primarily associated with traditional medicine practices in Europe, particularly in Italy and parts of Eastern Europe, is a genus of flowering plants. Traditionally, it has not been extensively used for medicinal purposes, though its use remains undocumented. Scientific evidence suggests that compounds from Anthyllis cytisoides, such as isorhamnetin-3-O-glucoside, exhibit anti-inflammatory properties by inhibiting COX-1, COX-2, and 5-LOX enzymes, but the strength of this evidence varies. Additionally, studies on intraspecific variability in resprouting after disturbance have shown that pre-disturbance plant size and aridity are significant factors, while immediate water availability has a lesser impact. There is also limited molecular genetic research indicating variable antimicrobial activity among different organs of extremophilic plants, though this does not specifically pertain to Anthyllis. Safety concerns for Anthyllis are currently non-existent, with no major issues recorded. Similarly, there have been no reported drug interactions associated with its use.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • Isorhamnetin-3-O-glucoside from Anthyllis cytisoides inhibits COX-1, COX-2, and 5-LOX with IC50 values of approximately 22.3, 31.6, and 31.9 μM, respectively. D PMID
  • Intraspecific variability in resprouting after disturbance was primarily driven by pre-disturbance plant size and secondarily by environmental factors. D PMID
  • The study provided new information on the structure and variability of plastid genomes in Loteae, placing Anthyllis within a resolved phylogenetic relationship. D PMID
  • The study characterized molecular diversity in extracts from different organs of four extremophilic plants and found variable antimicrobial activity against bacteria and fungi. D PMID

Frequently asked questions

What is Kidney-vetches?

Kidney-vetches (Anthyllis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Kidney-vetches?

4 sourced findings are recorded for Kidney-vetches; the strongest carries evidence grade D. For example: Isorhamnetin-3-O-glucoside from Anthyllis cytisoides inhibits COX-1, COX-2, and 5-LOX with IC50 values of approximately 22.3, 31.6, and 31.9 μM, respectively.

How strong is the evidence for Kidney-vetches?

The strongest finding for Kidney-vetches carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Kidney-vetches safe? What are the side effects?

No major safety issues are recorded for Kidney-vetches in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Kidney-vetches interact with medications?

No drug interactions are recorded for Kidney-vetches in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Kidney-vetches?

Kidney-vetches is also known as: Язвенник, Anthyllide.

Is Kidney-vetches a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Sixteen New Complete Plastid Genomes in the Tribe Loteae (Leguminosae): Structure and Phylogenetic Analysis. literature abstract metadata
  2. T2 Pre-disturbance plant condition drives intraspecific resprouting variability in Mediterranean shrubs. literature abstract metadata
  3. T2 Dual COX/5-LOX inhibition by isorhamnetin-3-O-glucoside from Anthyllis cytisoides: An integrated chemical-enzymatic-computational study. literature abstract metadata
  4. T2 Molecular diversity and antimicrobial properties of extracts from different organs of Tunisian extremophilic plants. literature abstract metadata