American-hemp

Apocynum cannabinum

Apocynum cannabinum, commonly known as Indian hemp or dogbane, is a plant native to North America. Traditionally, its use has not been extensively documented in specific medical practices, though it has been employed for various purposes such as fiber production and as an herbal remedy by some indigenous communities. Scientific evidence suggests that Apocynum cannabinum may have potential therapeutic applications. For instance, studies indicate that apocynin, a compound found in the plant, shows promise in treating certain disorders through multiple mechanisms, including inhibition of NADPH oxidase and modulation of signaling pathways. Additionally, naringenin and apocynin treatment were observed to significantly attenuate doxorubicin-induced cardiac toxicity in rats. A case report noted that combined homeopathic Apocynum cannabinum and increased furosemide led to partial remission in a patient with elephantiasis nostras over an 18-month period. No major safety concerns or drug interactions have been recorded for Apocynum cannabinum, but further research is needed to fully understand its potential benefits and risks.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • Beetles fed less on the nonnative Vincetoxicum rossicum compared to native Apocynum hosts, and while they laid eggs there, larvae did not survive beyond second instar. D PMID
  • Apocynin shows potential for treating various disorders through multiple mechanisms, including inhibition of NADPH oxidase and modulation of signaling pathways in different diseases. D PMID
  • Naringenin and apocynin treatment significantly attenuated doxorubicin-induced cardiac toxicity in rats. D PMID
  • The study found that treatment with increased furosemide and homeopathic Apocynum cannabinum led to partial remission in a patient with elephantiasis nostras over 18 months. D PMID

Frequently asked questions

What is American-hemp?

American-hemp (Apocynum cannabinum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about American-hemp?

4 sourced findings are recorded for American-hemp; the strongest carries evidence grade D. For example: Beetles fed less on the nonnative Vincetoxicum rossicum compared to native Apocynum hosts, and while they laid eggs there, larvae did not survive beyond second instar.

How strong is the evidence for American-hemp?

The strongest finding for American-hemp carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is American-hemp safe? What are the side effects?

No major safety issues are recorded for American-hemp in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does American-hemp interact with medications?

No drug interactions are recorded for American-hemp in our sources. This does not rule them out — check with a pharmacist.

What are the common names of American-hemp?

American-hemp is also known as: Кутра коноплёвая.

Is American-hemp a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Initial Response by a Native Beetle, Chrysochus auratus (Coleoptera: Chrysomelidae), to a Novel Introduced Host-Plant, Vincetoxicum rossicum (Gentianales: Apocynaceae). literature abstract metadata
  2. T2 Pharmacology of apocynin: a natural acetophenone. literature abstract metadata
  3. T2 An integrative therapeutic approach to elephantiasis nostras verrucosa: A case report. literature abstract metadata
  4. T2 Is the use of anthracyclines implicated in myocardial injury? Investigating the cardio modulatory effects of naringenin and apocynin in doxorubicin-induced cardiotoxicity in rats. literature abstract metadata