Paw Paws

Asimina

Asimina, commonly known as pawpaw, is a plant native to North America. Traditionally, its use has not been documented in any specific medical or healing practices. Scientific evidence primarily focuses on genetic research and potential therapeutic applications rather than traditional uses. A study involving spine arthrodesis and hip arthroplasty found no significant differences between the two procedures regarding postoperative complications and revisions. Additionally, a genome assembly of Asimina triloba has been developed, offering valuable resources for future research and breeding. Notably, a cyclopeptide named Asiminatide A from this plant showed promising results against triple-negative breast cancer in both laboratory and animal studies when delivered via a nanodrug system. Safety-wise, no major issues have been recorded, and there are currently no reported drug interactions associated with the use of Asimina.

At a glance
Best evidence
A
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • No significant differences were noted between spine arthrodesis followed by hip arthroplasty and hip arthroplasty followed by spine arthrodesis with respect to postoperative complications and revisions. A PMID
  • The study provides evidence for a late-acting self-incompatibility system in Asimina triloba, involving postzygotic embryo arrest and gene expression differences. D PMID
  • The study presents the first high-quality genome assembly of the pawpaw tree (Asimina triloba), providing genetic resources for future research and breeding. D PMID
  • A novel cyclopeptide Asiminatide A from Asimina triloba, delivered via a nanodrug system, showed enhanced efficacy against triple-negative breast cancer in vitro and in vivo. D PMID

Frequently asked questions

What is Paw Paws?

Paw Paws (Asimina) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Paw Paws?

4 sourced findings are recorded for Paw Paws; the strongest carries evidence grade A. For example: No significant differences were noted between spine arthrodesis followed by hip arthroplasty and hip arthroplasty followed by spine arthrodesis with respect to postoperative complications and revisions.

How strong is the evidence for Paw Paws?

The strongest finding for Paw Paws carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Paw Paws safe? What are the side effects?

No major safety issues are recorded for Paw Paws in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Paw Paws interact with medications?

No drug interactions are recorded for Paw Paws in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Paw Paws?

Paw Paws is also known as: Азимина.

Is Paw Paws a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Late-acting self-incompatibility in Asimina triloba: implications for the evolution of self-incompatibility in angiosperms. literature abstract metadata
  2. T2 Enhanced Anticancer Efficacy of Novel Asiminatide A Isolated from Asimina triloba in Triple-Negative Breast Cancer. literature abstract metadata
  3. T2 First genome and transcription factor profile for Asimina triloba, a native North American fruit tree. literature abstract metadata
  4. T2 Impact of Operative Order on Postoperative Outcomes in Patients Undergoing Lumbar Fusion and Total Hip Arthroplasty: A Systematic Review and Meta-Analysis. literature abstract metadata