Domestic silk moth

Bombyx mori

Bombyx mori, commonly known as the domestic silkmoth, is a traditional subject of study and application in sericulture but has no recorded historical medicinal uses. Scientific research on Bombyx mori derivatives suggests potential applications; for instance, SGH2, an HMBI derivative, demonstrates larvicidal activity by disrupting juvenile hormone signaling pathways, which may influence diapause incidence in silkworm eggs. Additionally, a catalytically inactive Bombyx mori serine protease binds and sequesters mulberry tree protease inhibitors, potentially affecting larval growth. A fructose-sensitive gustatory receptor has been linked to nutrient availability influencing hematopoietic output through an Akt-dependent pathway. While no major safety issues or drug interactions have been recorded, the current evidence is limited and primarily focused on silkworm biology rather than human health applications.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • A catalytically inactive Bombyx mori serine protease binds and sequesters plant protease inhibitors, potentially as an adaptive strategy. D PMID
  • SGH2, an HMBI derivative, shows larvicidal activity against Bombyx mori by disrupting juvenile hormone signaling. D PMID
  • The study suggests that BmAR may modulate sorbitol levels, influencing diapause incidence in silkworm eggs. D PMID
  • A fructose-sensitive gustatory receptor links nutrient availability to hematopoietic output in silkworms. D PMID

Frequently asked questions

What is Domestic silk moth?

Domestic silk moth (Bombyx mori) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Domestic silk moth?

4 sourced findings are recorded for Domestic silk moth; the strongest carries evidence grade D. For example: A catalytically inactive Bombyx mori serine protease binds and sequesters plant protease inhibitors, potentially as an adaptive strategy.

How strong is the evidence for Domestic silk moth?

The strongest finding for Domestic silk moth carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Domestic silk moth safe? What are the side effects?

No major safety issues are recorded for Domestic silk moth in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Domestic silk moth interact with medications?

No drug interactions are recorded for Domestic silk moth in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Domestic silk moth?

Domestic silk moth is also known as: тутовый шелкопряд, Bombyx du mûrier.

Is Domestic silk moth a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 A gustatory receptor-Akt axis couples nutrient sensing to hematopoiesis in the silkworm. literature abstract metadata
  2. T2 Decoy digestive protease strategy in Bombyx mori: Catalytically inactive BmoSPH12723 sequesters mulberry protease inhibitor by a C-terminal compositionally biased region. literature abstract metadata
  3. T2 Aldehyde reductase via sorbitol synthesis alters diapause incidence in silkworm eggs. literature abstract metadata
  4. T2 Biological activity of 2-methylbenzimidazole derivatives with heterocyclic rings on development of Bombyx mori. literature abstract metadata