Bridelia retusa
Bridelia retusa
Bridelia retusa is a plant traditionally used in various folk medicine practices, particularly in Southeast Asia and parts of Africa. It has been employed for its purported anti-inflammatory properties and to treat joint pain, although specific traditional uses are not extensively documented. Scientific evidence suggests that compounds from Bridelia retusa, such as ellagic acid and (+)-sesamin, may have potential antiviral activity against SARS-CoV-2 through in silico studies. Additionally, silver nanoparticles synthesized from the leaf extracts of this plant show promise in inhibiting biofilm formation by certain pathogens. The bark extracts exhibit significant analgesic, anti-inflammatory, and anti-arthritic effects in animal models. However, there is no substantial evidence to support these claims in human clinical trials. Safety profiles for Bridelia retusa are currently favorable with no major issues recorded, and there are no reported drug interactions as of the current knowledge base.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified ellagic acid and (+)-sesamin from Bridelia retusa as potential inhibitors of SARS-CoV-2 3CL pro through in silico techniques.
- The study found that silver nanoparticles synthesized from Bridelia retusa leaf extracts showed potential anti-biofilm activity against certain human pathogens.
- Bridelia retusa bark extracts showed significant analgesic, anti-inflammatory, and anti-arthritic activity in animal models.
- The study found that pinocembrin-7-O-β-D-glucopyranoside from Acacia pennata had the most stable complex with β-lactamase, potentially inhibiting it to combat antibiotic resistance.
Frequently asked questions
What is Bridelia retusa?
Bridelia retusa (Bridelia retusa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bridelia retusa?
4 sourced findings are recorded for Bridelia retusa; the strongest carries evidence grade D. For example: The study identified ellagic acid and (+)-sesamin from Bridelia retusa as potential inhibitors of SARS-CoV-2 3CL pro through in silico techniques.
How strong is the evidence for Bridelia retusa?
The strongest finding for Bridelia retusa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bridelia retusa safe? What are the side effects?
No major safety issues are recorded for Bridelia retusa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bridelia retusa interact with medications?
No drug interactions are recorded for Bridelia retusa in our sources. This does not rule them out — check with a pharmacist.
Is Bridelia retusa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Evaluation of analgesic and anti-inflammatory activity of Bridelia retusa (Spreng) bark. literature abstract metadata
- T2 Anti-biofilm and Antibacterial Activities of Silver Nanoparticles Synthesized by the Reducing Activity of Phytoconstituents Present in the Indian Medicinal Plants. literature abstract metadata
- T2 Antiviral phytocompounds "ellagic acid" and "(+)-sesamin" of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive molecular docking, molecular dynamics simulation studies, binding free energy calculations literature abstract metadata
- T2 In-silico screening of Acacia pennata and Bridelia retusa reveals pinocembrin-7-O-β-D-glucopyranoside as a promising β-lactamase inhibitor to combat antibiotic resistance. literature abstract metadata