Canarium album
Canarium album
Canarium album, commonly known as Chinese olive, is a traditional plant used in various Asian cultures. While its specific medicinal uses are not well-documented, studies suggest potential benefits related to gut health and inflammation. Polyphenols from Canarium album have been shown to increase Bifidobacterium abundance and alter the relative abundance of other bacterial genera in different gut microbiota profiles across healthy individuals, those with ulcerative colitis (UC), and those with Crohn's disease (CD). Additionally, polyphenol-rich extracts reduced lipid accumulation in liver cells through AMPK phosphorylation and miRNA modulation. Research also indicates that Canarium album may reduce inflammatory mediator release and expressions of COX-2 and iNOS via downregulating the MAPK signaling pathway. No major safety issues or drug interactions have been recorded, but further research is needed to confirm these findings comprehensively.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Polyphenols from Canarium album increased Bifidobacterium abundance while altering the relative abundance of other bacterial genera in different gut microbiota profiles across healthy, UC, and CD individuals.
- Polyphenol-rich Chinese olive extracts reduced lipid accumulation in HepG2 cells through AMPK phosphorylation and miRNA modulation.
- RPN2B and NIFS1 were identified as consistently stable reference genes across different varieties and developmental stages of Canarium album fruits.
- This study suggests Canarium album may reduce inflammatory responses via downregulating MAPK signaling in cigarette smoke-induced Beas-2B cells, though specific active components need further validation.
- The leaves of Canarium album showed anti-influenza activities by suppressing the PI3K/AKT signaling pathway in cell and mouse models.
Frequently asked questions
What is Canarium album?
Canarium album (Canarium album) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Canarium album?
5 sourced findings are recorded for Canarium album; the strongest carries evidence grade D. For example: Polyphenols from Canarium album increased Bifidobacterium abundance while altering the relative abundance of other bacterial genera in different gut microbiota profiles across healthy, UC, and CD individuals.
How strong is the evidence for Canarium album?
The strongest finding for Canarium album carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Canarium album safe? What are the side effects?
No major safety issues are recorded for Canarium album in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Canarium album interact with medications?
No drug interactions are recorded for Canarium album in our sources. This does not rule them out — check with a pharmacist.
Is Canarium album a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 The leaves of Canarium album (Lour.) DC. suppresses influenza A virus replication and inflammation through modulation of PI3K-AKT pathway. literature abstract metadata
- T2 qPCR-Based Reference Gene Validation in Canarium album: Stability Across Varieties and Developmental Stages. literature abstract metadata
- T2 Protective Effects of Canarium album Against Cigarette Smoke-Induced Cytotoxicity in Beas-2B Cells: Bioactive Components Screening and Mechanism Exploring. literature abstract metadata
- T2 Polyphenol-rich Chinese olive extracts attenuate lipid accumulation in HepG2 cells, accompanied by AMPK phosphorylation and miRNA alterations. literature abstract metadata
- T2 Interaction between Chinese olive (Canarium album L.) polyphenols and gut microbiota: Potential implications for inflammatory bowel disease. literature abstract metadata