Spreading Sneezeweed
Centipeda minima
Centipeda minima is a plant traditionally used in Australian Aboriginal medicine. While specific traditional uses are not well-documented, it has been associated with various applications based on local knowledge and practices. Scientific evidence suggests potential anti-cancer properties, particularly in inhibiting the proliferation and metastasis of liver cancer cells through modulation of PI3K/Akt and MAPK pathways. Additionally, brevilin A from Centipeda minima may suppress colorectal adenoma-to-adenocarcinoma transition by regulating NR1D1/APOH signaling and reducing lipid accumulation. The plant also contains enzymes involved in triterpene biosynthesis, indicating a complex chemical profile. Notably, no major safety concerns or recorded drug interactions have been identified to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This review identifies potential quality markers for Centipeda minima based on its chemical composition and traditional uses.
- AC from Centipeda minima inhibits HCC cell proliferation and metastasis by modulating PI3K/Akt and MAPK pathways via ROS accumulation.
- Brevilin A from Centipeda minima suppressed colorectal adenoma-to-adenocarcinoma transition by modulating NR1D1/APOH signaling, reducing lipid accumulation.
- Six 2,3-oxidosqualene cyclases and three cytochrome P450 enzymes were identified in Centipeda minima, involved in triterpene biosynthesis.
Frequently asked questions
What is Spreading Sneezeweed?
Spreading Sneezeweed (Centipeda minima) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Spreading Sneezeweed?
4 sourced findings are recorded for Spreading Sneezeweed; the strongest carries evidence grade D. For example: This review identifies potential quality markers for Centipeda minima based on its chemical composition and traditional uses.
How strong is the evidence for Spreading Sneezeweed?
The strongest finding for Spreading Sneezeweed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Spreading Sneezeweed safe? What are the side effects?
No major safety issues are recorded for Spreading Sneezeweed in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Spreading Sneezeweed interact with medications?
No drug interactions are recorded for Spreading Sneezeweed in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Spreading Sneezeweed?
Spreading Sneezeweed is also known as: Стоножка малая.
Is Spreading Sneezeweed a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Oxidosqualene cyclases and cytochrome P450s involved in the biosynthesis of diverse triterpenes in Centipeda minima. literature abstract metadata
- T2 Brevilin A suppresses lipid metabolism reprogramming in colorectal adenoma-to-adenocarcinoma sequence via the NR1D1/APOH signaling axis. literature abstract metadata
- T2 Arnicolide C induces ROS-mediated modulation of PI3K/Akt and MAPK pathways to suppress MYC in hepatocellular carcinoma. literature abstract metadata
- T2 Centipeda minima: A Review of Phytochemistry, Pharmacology, and Predictive Analysis on Quality Markers. literature abstract metadata