Yan Hu Suo
Corydalis yanhusuo
Corydalis yanhusuo is a traditional Chinese medicinal plant used in East Asian practices, particularly for pain relief and to regulate menstruation. Scientific evidence suggests its active compounds may have anti-cancer properties, showing potential against prostate cancer cells by inhibiting specific signaling pathways. Additionally, Corydalis yanhusuo has demonstrated anti-atherosclerotic effects and neuroprotective benefits, though the mechanisms are still being explored. While no major safety issues or drug interactions have been reported, further research is needed to fully understand its therapeutic potential and ensure safe use.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- THP and PRO are inhibitors of CYP2D6, potentially leading to drug-drug interactions.
- DHC from Corydalis yanhusuo exerted significant antiatherosclerotic effects by modulating the STAT3/Bcl-2 axis to attenuate apoptosis and enhance efferocytosis in atherosclerotic mice.
- CDY exhibits anti-cancer effects by targeting multiple signaling pathways involved in prostate cancer progression.
- Dehydrocorydaline from Corydalis yanhusuo reduces neuroinflammation and improves neurological function after cerebral ischemia-reperfusion injury by promoting M2 microglial polarization.
Frequently asked questions
What is Yan Hu Suo?
Yan Hu Suo (Corydalis yanhusuo) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Yan Hu Suo?
4 sourced findings are recorded for Yan Hu Suo; the strongest carries evidence grade D. For example: THP and PRO are inhibitors of CYP2D6, potentially leading to drug-drug interactions.
How strong is the evidence for Yan Hu Suo?
The strongest finding for Yan Hu Suo carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Yan Hu Suo safe? What are the side effects?
No major safety issues are recorded for Yan Hu Suo in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Yan Hu Suo interact with medications?
No drug interactions are recorded for Yan Hu Suo in our sources. This does not rule them out — check with a pharmacist.
Is Yan Hu Suo a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Dehydrocorydaline in Corydalis Yanhusuo Promotes M2 Microglial Polarization and Alleviates Neuroinflammation After Cerebral Ischemia-Reperfusion Injury by Inhibiting the JAK1/STAT3 Pathway. literature abstract metadata
- T2 Dehydrocorydaline Promotes STAT3/Bcl-2 Axis-Mediated Macrophage Efferocytosis to Attenuate Apoptosis in Atherosclerotic Plaques. literature abstract metadata
- T2 Inhibition of human liver cytochrome P450 2D6 (CYP6D2) by tetrahydropalmatine, protopine, and dehydrocorydaline and their oxidative metabolism. literature abstract metadata
- T2 Mechanistic investigation of Corydalis yanhusuo in prostate cancer: Targeting the miR-192-5p-PI3K/AKT/mTOR and STAT3-HSP90 pathways. literature abstract metadata