Diospyros malabarica
Diospyros malabarica
Diospyros malabarica, commonly known as Malabar persimmon or Indian date, is a traditional plant used primarily in Ayurvedic and other indigenous practices of South Asia. While its specific uses are not extensively documented, studies have shown that fruit preparations enhance dendritic cell maturation and upregulate TH1 cytokine secretion, indicating potential immune-modulatory effects. Additionally, the methanol extract from the fruit demonstrated anti-inflammatory properties by modulating biomarkers in rat models, suggesting possible therapeutic applications for inflammation-related conditions. The methanol extract was also effective in extracting phytochemicals with biological activities from the bark of the plant and showed potential hepatoprotective effects in rats through modulation of liver function parameters. Safety-wise, no major issues have been recorded, and there are currently no known drug interactions associated with Diospyros malabarica.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Diospyros malabarica fruit preparation (DFP) upregulates TH1 cytokine secretion and p53 expression while downregulating TH2 cytokines, potentially evoking tumor protective immunity.
- The methanol extract of Diospyros malabarica fruit showed anti-inflammatory effects by modulating pro- and anti-inflammatory biomarkers in rat models.
- The study found that quercetin from Diospyros malabarica fruits showed potential hepatoprotective effects by modulating liver function parameters and signaling proteins in rats.
- The study found that methanol was the most effective solvent for extracting phytochemicals and biological activities from Diospyros malabarica bark.
Frequently asked questions
What is Diospyros malabarica?
Diospyros malabarica (Diospyros malabarica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Diospyros malabarica?
4 sourced findings are recorded for Diospyros malabarica; the strongest carries evidence grade D. For example: Diospyros malabarica fruit preparation (DFP) upregulates TH1 cytokine secretion and p53 expression while downregulating TH2 cytokines, potentially evoking tumor protective immunity.
How strong is the evidence for Diospyros malabarica?
The strongest finding for Diospyros malabarica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Diospyros malabarica safe? What are the side effects?
No major safety issues are recorded for Diospyros malabarica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Diospyros malabarica interact with medications?
No drug interactions are recorded for Diospyros malabarica in our sources. This does not rule them out — check with a pharmacist.
Is Diospyros malabarica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Nonlinear molecular dynamics of quercetin in Gynocardia odorata and Diospyros malabarica fruits: Its mechanistic role in hepatoprotection. literature abstract metadata
- T2 A Comparative Study of Diospyros malabarica (Gaub) Extracts in Various Polarity-Dependent Solvents for Evaluation of Phytoconstituents and Biological Activities. literature abstract metadata
- T2 Diospyros malabarica (Desr.) Kostel fruits extract attenuated acute and chronic inflammation through modulation of the expression of pro- and anti-inflammatory biomarkers in rat models. literature abstract metadata
- T2 Diospyros malabarica fruit preparation mediates immunotherapeutic modulation and epigenetic regulation to evoke protection against non-small cell lung cancer (NSCLC). literature abstract metadata