Drynaria roosii
Drynaria roosii
Drynaria roosii, a traditional Chinese medicine plant native to East Asia, is primarily used in herbal remedies and has a long history of application. While its specific traditional uses are not well-documented, studies have shown promising results with extracts from the plant. Scientific evidence indicates that Drynaria roosii can significantly increase bone mineral density and improve trabecular microarchitecture in rat models of osteoporosis, suggesting potential benefits for bone health. Additionally, it has been found to reduce iron accumulation and ferroptosis-related indicators, accelerate bone defect healing, and enhance osteogenesis-related factors expression. The plant also promotes alveolar socket healing by enhancing calcium flux via ITPR3 activation. However, the current body of research is limited, and more human studies are needed to confirm these findings. No major safety issues or drug interactions have been recorded, but further investigation is warranted given its potential therapeutic benefits.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Drynaria roosii extracts significantly increased bone mineral density and improved trabecular microarchitecture in rat models of osteoporosis.
- Treatment with TFRD and DMF reduced iron accumulation and ferroptosis-related indicators, accelerated bone defect healing, and enhanced osteogenesis-related factors expression.
- The study identified key genes involved in the biosynthesis of flavonoids in Drynaria roosii, particularly in its tuber.
- Drynaria roosii-derived exosome-like nanovesicles promote alveolar socket healing by enhancing calcium flux via ITPR3 activation.
Frequently asked questions
What is Drynaria roosii?
Drynaria roosii (Drynaria roosii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Drynaria roosii?
4 sourced findings are recorded for Drynaria roosii; the strongest carries evidence grade A. For example: Drynaria roosii extracts significantly increased bone mineral density and improved trabecular microarchitecture in rat models of osteoporosis.
How strong is the evidence for Drynaria roosii?
The strongest finding for Drynaria roosii carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Drynaria roosii safe? What are the side effects?
No major safety issues are recorded for Drynaria roosii in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Drynaria roosii interact with medications?
No drug interactions are recorded for Drynaria roosii in our sources. This does not rule them out — check with a pharmacist.
Is Drynaria roosii a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Integrative transcriptomic and metabolomic analysis of Drynaria roosii reveals genes involved in the biosynthesis of medicinal compounds. literature abstract metadata
- T2 Total flavonoids of Rhizoma drynariae targets NRF2-mediated anti-ferroptosis in osteoblasts to promote induced membrane osteogenesis. literature abstract metadata
- T2 Efficacy of Rhizoma Drynariae (Drynaria roosii Nakaike) extracts in treating osteoporosis in rat models: A systematic review and meta-analysis. literature abstract metadata
- T2 Drynaria roosii-derived exosome-like nanovesicles promote alveolar socket healing via activation of ITPR3-mediated calcium flux. literature abstract metadata