Five-fingered Aralia
Eleutherococcus sieboldianus
Eleutherococcus sieboldianus, also known as Siberian Ginseng, is a plant traditionally used in East Asian medicine, particularly in Traditional Chinese Medicine. It has been employed for its purported adaptogenic and immunomodulatory properties, though specific traditional uses are not well-documented. Scientific evidence suggests that compounds from the leaves and stem barks of related species, such as Acanthopanax evodiaefolius (which is closely related to Eleutherococcus sieboldianus), exhibit anti-inflammatory activity and affect lipid accumulation in cells. Similarly, studies have isolated terpene synthase genes from E. sieboldianus, indicating potential bioactive compounds. However, direct evidence linking these findings specifically to E. sieboldianus is limited. Safety profiles for the plant are generally favorable with no major issues recorded, and there are currently no known drug interactions associated with its use.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The gut microbiota diversity in adult male golden snub-nosed monkeys decreased during food shortages and parturition-nursing periods.
- The liposoluble constituents from leaves and stem barks of Acanthopanax evodiaefolius showed significant anti-inflammatory activity.
- Two compounds from Eleutherococcus sieboldianus regulated lipid accumulation in preadipocytes, with one increasing and another decreasing it.
- The study isolated and characterized TPS genes from three edible plants, including Eleutherococcus sieboldianus, which encode for various β-caryophyllene synthases and other terpene synthases.
Frequently asked questions
What is Five-fingered Aralia?
Five-fingered Aralia (Eleutherococcus sieboldianus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Five-fingered Aralia?
4 sourced findings are recorded for Five-fingered Aralia; the strongest carries evidence grade D. For example: The gut microbiota diversity in adult male golden snub-nosed monkeys decreased during food shortages and parturition-nursing periods.
How strong is the evidence for Five-fingered Aralia?
The strongest finding for Five-fingered Aralia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Five-fingered Aralia safe? What are the side effects?
No major safety issues are recorded for Five-fingered Aralia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Five-fingered Aralia interact with medications?
No drug interactions are recorded for Five-fingered Aralia in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Five-fingered Aralia?
Five-fingered Aralia is also known as: Элеутерококк Зибольда, éleuthérocoque à cinq folioles.
Is Five-fingered Aralia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Chemical composition, anti-inflammatory activity and cytotoxic activity of the liposoluble constituents from different parts of Acanthopanax evodiaefolius by the Herbal Blitzkrieg Extractor. literature abstract metadata
- T2 Effects of Flavonoids and Triterpene Analogues from Leaves of Eleutherococcus sieboldianus (Makino) Koidz. 'Himeukogi' in 3T3-L1 Preadipocytes. literature abstract metadata
- T2 Isolation and Functional Characterization of New Terpene Synthase Genes from Traditional Edible Plants. literature abstract metadata
- T2 Gut microbiota alterations in golden snub-nosed monkeys during food shortage and parturition-nursing periods. literature abstract metadata