false black pepper
Embelia ribes
Embelia ribes is a plant traditionally used in certain Asian and Indian herbal practices. While specific traditional uses are not well-documented, it has been studied for its potential medicinal properties. Scientific evidence suggests that 5-O-Methylembelin from Embelia ribes can induce ferroptosis in clear cell renal cell carcinoma (ccRCC) cells by disrupting the ACO1-TPI1 interaction and shows promise as an anticancer agent. Additionally, a study found that an Embelin-Sn complex synthesized from its fruits exhibited potential anticancer and antibacterial activities in vitro. Furthermore, extracts containing Embelia ribes demonstrated significant antidiabetic effects without adverse side effects in toxicity studies. Safety concerns are minimal based on current data, with no major issues or recorded drug interactions noted.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- 5-O-Methylembelin induces ferroptosis in clear cell renal cell carcinoma by disrupting the ACO1-TPI1 interaction.
- Epigenetic modulators AZ and SB altered the metabolite profiles of endophytes from Embelia ribes, activating silent metabolites and enhancing production of certain compounds.
- The study synthesized and characterized an Embelin-Sn complex from Embelia ribes fruits, showing potential anticancer and antibacterial activities in vitro.
- NPF, containing Embelia ribes among other herbs, showed significant antidiabetic potential with no adverse effects in toxicity studies.
Frequently asked questions
What is false black pepper?
false black pepper (Embelia ribes) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about false black pepper?
4 sourced findings are recorded for false black pepper; the strongest carries evidence grade D. For example: 5-O-Methylembelin induces ferroptosis in clear cell renal cell carcinoma by disrupting the ACO1-TPI1 interaction.
How strong is the evidence for false black pepper?
The strongest finding for false black pepper carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is false black pepper safe? What are the side effects?
No major safety issues are recorded for false black pepper in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does false black pepper interact with medications?
No drug interactions are recorded for false black pepper in our sources. This does not rule them out — check with a pharmacist.
Is false black pepper a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Therapeutic potential of novel tin metal complex of embelin isolated from Embelia ribes fruits. literature abstract metadata
- T2 Pharmacokinetic, toxicological, and antidiabetic evaluation of a novel polyherbal formulation. literature abstract metadata
- T2 Effect of epigenetic modulation on metabolites from endophytes isolated from Embelia ribes. literature abstract metadata
- T2 5-O-Methylembelin disrupts the ACO1-TPI1 interaction to promote ferroptosis in clear cell renal cell carcinoma. literature abstract metadata