Korean barrenwort
Epimedium koreanum
Epimedium koreanum, a traditional plant with roots in East Asian medicine, has not been extensively documented for specific uses. Scientific studies have revealed that it contains various bioactive compounds with multiple pharmacological effects, supporting some of its traditional applications while also highlighting potential toxicity concerns. Research indicates that forest-cultivated Epimedium koreanum Nakai can provide superior protection against organotin-induced renal injury and diabetic nephropathy by activating the SIRT1/NRF2/PPARγ signaling pathway. Additionally, an endophytic fungus from Korean Epimedium Nakai has been shown to promote Arabidopsis thaliana growth through increased root length and lateral root numbers. EKPA (Epimedium koreanum polysaccharide) demonstrated potential in improving liver function and reducing oxidative stress in diabetic rats via the NRF2/HO-1 pathways. No major safety issues or drug interactions have been recorded, but further research is needed to fully understand its efficacy and safety profile.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that Epimedium koreanum contains various compounds with multiple pharmacological effects, supporting some traditional uses but highlighting potential toxicity concerns.
- Forest-cultivated Epimedium koreanum Nakai provides superior protection against organotin-induced renal injury and diabetic nephropathy by activating the SIRT1/NRF2/PPARγ signaling pathway.
- The endophytic fungus Colletotrichum endophyticum (Y8) from Korean Epimedium Nakai promoted Arabidopsis thaliana growth by increasing root length and lateral root numbers.
- EKB exhibits potent cytotoxicity against multiple myeloma cells by stabilizing G4 structures of key oncogenes.
- EKPA from Epimedium koreanum showed dose-dependent improvement in liver function and blood parameters in diabetic rats.
Frequently asked questions
What is Korean barrenwort?
Korean barrenwort (Epimedium koreanum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Korean barrenwort?
5 sourced findings are recorded for Korean barrenwort; the strongest carries evidence grade A. For example: The study found that Epimedium koreanum contains various compounds with multiple pharmacological effects, supporting some traditional uses but highlighting potential toxicity concerns.
How strong is the evidence for Korean barrenwort?
The strongest finding for Korean barrenwort carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Korean barrenwort safe? What are the side effects?
No major safety issues are recorded for Korean barrenwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Korean barrenwort interact with medications?
No drug interactions are recorded for Korean barrenwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Korean barrenwort?
Korean barrenwort is also known as: Эпимедиум корейский.
Is Korean barrenwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 A systematic review of traditional uses, phytochemistry, pharmacology and toxicity of Epimedium koreanum Nakai. literature abstract metadata
- T2 Directly targeting G-quadruplexes contributes to the anti-multiple myeloma efficacy of Epimedokoreanin B. literature abstract metadata
- T2 Structure analysis of an acidic polysaccharide isolated from Epimedium koreanum Nakai and its improvement on liver oxidative stress injury in STZ-induced diabetic rats via NRF2/HO-1 pathways. literature abstract metadata
- T2 The endogenous fungus Colletotrichum endophyticum from Korean epimedium Nakai promoted the growth of the model plant Arabidopsis thaliana. literature abstract metadata
- T2 Forest-cultivated Epimedium koreanum Nakai mitigates organotin-induced renal injury and the exacerbation of diabetic nephropathy via the SIRT1/NRF2/PPARγ signaling pathways. literature abstract metadata