Gutta percha

Eucommia ulmoides

Eucommia ulmoides, a traditional Chinese medicinal plant, is traditionally not associated with specific uses in its native regions. Scientific evidence suggests that Eucommia ulmoides bark extract may enhance immune responses and improve cardiac function, particularly in conditions like diabetic cardiomyopathy. Studies have also shown improvements in growth performance and rumen microbiome composition when 5% of the diet consists of Eucommia ulmoides leaves for sheep. The aqueous extract has been found to be safe through various safety assessments for cosmetic use, with no significant concerns reported. There is currently no evidence of major safety issues or drug interactions associated with Eucommia ulmoides; however, further research is needed to fully understand its potential applications and effects.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • DEC-205-EUPS-OVA-LP enhanced dendritic cell function and immune responses through TLR-NF-κB pathway activation. D PMID
  • Feeding 5% Eucommia ulmoides leaves to sheep improved growth performance and altered the rumen microbiome, increasing butyrate-producing bacteria abundance. D PMID
  • The study found no significant concerns regarding the local or systemic safety of aqueous Eucommia ulmoides bark extract for cosmetic use through various safety assessments. D PMID
  • PDG from Eucommia ulmoides reduced cardiac hypertrophy, inflammation, and apoptosis in diabetic cardiomyopathy by downregulating STIM1/Orai1/NFAT3 signaling. D PMID
  • A high-performance photoelectrochemical sensor was developed using in situ grown ZnIn2S4@ZnWO4 heterojunctions for detecting chlorogenic acid, showing good linear relationships and low detection limits. D PMID

Frequently asked questions

What is Gutta percha?

Gutta percha (Eucommia ulmoides) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Gutta percha?

5 sourced findings are recorded for Gutta percha; the strongest carries evidence grade D. For example: DEC-205-EUPS-OVA-LP enhanced dendritic cell function and immune responses through TLR-NF-κB pathway activation.

How strong is the evidence for Gutta percha?

The strongest finding for Gutta percha carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Gutta percha safe? What are the side effects?

No major safety issues are recorded for Gutta percha in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Gutta percha interact with medications?

No drug interactions are recorded for Gutta percha in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Gutta percha?

Gutta percha is also known as: Эвкоммия, Arbre à gomme.

Is Gutta percha a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 DEC-205-mediated liposomal delivery of OVA and Eucommia polysaccharides: dendritic cell targeting, adjuvant activity, and TLR-NF-κB-mediated immune enhancement. literature abstract metadata
  2. T2 In Situ Grown ZnIn2S4@ZnWO4 Heterojunction for Highly Sensitive Photoelectrochemical Detection of Chlorogenic Acid. literature abstract metadata
  3. T2 Assessment of local and systemic safety of aqueous Eucommia ulmoides bark extract for a cosmetics ingredient utilizing in vitro, in silico, threshold of toxicological concern and history of safe use approaches. literature abstract metadata
  4. T2 Eucommia ulmoides leaves improving growth by regulating the rumen microbiome in sheep. literature abstract metadata
  5. T2 Pinoresinol diglucoside from Eucommia ulmoides attenuates diabetic cardiomyopathy through suppressing the store-operated calcium entry and downregulating the STIM1/Orai1/NFAT3 signaling pathway. literature abstract metadata