Eurycoma longifolia

Eurycoma longifolia, commonly known as Tongkat Ali in Malaysia, is a traditional medicinal plant used primarily in Southeast Asian countries. Traditionally, it has been employed for various purposes such as enhancing male sexual function and general well-being, though specific recorded uses vary among different cultures. Scientific evidence suggests that the roots of Eurycoma longifolia contain twenty-six identified compounds, with four showing anti-inflammatory activity. Additionally, two compounds demonstrated dose-dependent inhibitory effects against Blastocystis ST3 and ST7. The plant also yielded three new C20 quassinoids, eurycomanoic acids A-C, which have been isolated from its roots. In preliminary studies, Eurycoma longifolia polysaccharides extended the lifespan and healthspan of nematodes (C. elegans) and fruit flies (D. melanogaster), reducing age-associated accumulations and activating longevity pathways. Safety findings indicate no major issues recorded; however, further research is needed to confirm these results comprehensively. There are currently no reported drug interactions associated with Eurycoma longifolia, but caution should be exercised given the limited data available.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.