Garcinia
Garcinia xanthochymus
Garcinia xanthochymus is a plant traditionally found in Southeast Asia. While its use in traditional medicine has not been extensively documented, studies have shown promising results for certain compounds derived from this plant. In vitro research indicates strong antioxidant and antidiabetic activities from the ethyl acetate fraction of Garcinia xanthochymus. Additionally, the chloroplast genome of the plant was sequenced, providing insights into its phylogenetic relationships and structure. Notably, 1,4,5,6-tetrahydroxy-7,8-diprenylxanthone demonstrated inhibitory effects against cells with specific EGFR mutations. Six new compounds were identified from Garcinia xanthochymus, one of which showed moderate cytotoxic activity. To date, no significant safety concerns or drug interactions have been reported for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The ethyl acetate fraction of Garcinia xanthochymus showed strong in vitro antioxidant and antidiabetic activities.
- The study sequenced the chloroplast genome of Garcinia xanthochymus, revealing its structure and providing insights into its phylogenetic relationships.
- 1,4,5,6-tetrahydroxy-7,8-diprenylxanthone from Garcinia xanthochymus showed inhibitory effects against NSCLC cells with L858R/T790M/C797S mutant EGFR.
- The study identified six new compounds from Garcinia xanthochymus and revised the structures of seven analogues.
Frequently asked questions
What is Garcinia?
Garcinia (Garcinia xanthochymus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Garcinia?
4 sourced findings are recorded for Garcinia; the strongest carries evidence grade D. For example: The ethyl acetate fraction of Garcinia xanthochymus showed strong in vitro antioxidant and antidiabetic activities.
How strong is the evidence for Garcinia?
The strongest finding for Garcinia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Garcinia safe? What are the side effects?
No major safety issues are recorded for Garcinia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Garcinia interact with medications?
No drug interactions are recorded for Garcinia in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Garcinia?
Garcinia is also known as: Faux mangoustanier, Mangoustan jaune-aigre, Mangoustan sauvage.
Is Garcinia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Inhibitory effect of 1,4,5,6-tetrahydroxy-7,8-diprenylxanthone against NSCLC with L858R/T790M/C797S mutant EGFR. literature abstract metadata
- T2 Characterization of the complete chloroplast genome of Garcinia xanthochymus Hook. f. ex T. Anderson 1874 (Clusiaceae) and its phylogenetic implications. literature abstract metadata
- T2 Polyprenylated acylphloroglucinols from Garcinia species and structural revision of seven analogues. literature abstract metadata
- T2 Exploring antioxidant properties and antidiabetic potential of ten underutilized Sri Lankan fruits. literature abstract metadata