Guarea
Guarea
Guarea is a genus of plants primarily found in tropical and subtropical regions, particularly Central and South America. While traditional uses for specific species within this genus are not well-documented, some species have shown potential biological activities. For instance, extracts from Guarea guidonia roots and Anadenanthera colubrina leaves demonstrated significant inhibitory effects on plant growth. Additionally, studies indicate that extracts from Piper nigrum, Albizia ferruginea, and Guarea cedrata exhibit varying levels of anthelmintic activity against nematodes in vitro. Spathulenol, isolated from Guarea macrophylla, displayed potent and selective in vitro anthelmintic activity against Angiostrongylus cantonensis larvae. The soil microbiome's influence on leaf heat tolerance was also observed differently under warming compared to ambient conditions for Guarea guidonia seedlings. Currently, there is no substantial evidence of major safety concerns or recorded drug interactions associated with the use of Guarea species. However, further research is necessary to fully understand their potential applications and effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that extracts from Guarea guidonia roots and Anadenanthera colubrina leaves showed significant inhibitory effects on target plant growth.
- The study found that extracts from Piper nigrum, Albizia ferruginea, and Guarea cedrata showed varying levels of anthelmintic activity against nematodes in vitro.
- Spathulenol, isolated from Guarea macrophylla, showed potent in vitro anthelmintic activity against Angiostrongylus cantonensis larvae with selectivity.
- The soil microbiome influenced leaf heat tolerance differently under warming compared to ambient conditions in Guarea guidonia seedlings.
Frequently asked questions
What is Guarea?
Guarea (Guarea) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Guarea?
4 sourced findings are recorded for Guarea; the strongest carries evidence grade D. For example: The study found that extracts from Guarea guidonia roots and Anadenanthera colubrina leaves showed significant inhibitory effects on target plant growth.
How strong is the evidence for Guarea?
The strongest finding for Guarea carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Guarea safe? What are the side effects?
No major safety issues are recorded for Guarea in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Guarea interact with medications?
No drug interactions are recorded for Guarea in our sources. This does not rule them out — check with a pharmacist.
Is Guarea a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Tropical Forest Soil Microbiome Modulates Leaf Heat Tolerance More Strongly Under Warming Than Ambient Conditions. literature abstract metadata
- T2 Anthelminthic Activity of Piper nigrum, Albizia ferruginea, and Guarea cedrata Against Caenorhabditis elegans and Heligmosomoides polygyrus: In Vitro and In Silico Molecular Docking Approach. literature abstract metadata
- T2 New perspectives on the allelopathic potential of Brazilian Atlantic Forest native trees. literature abstract metadata
- T2 Spathulenol, a Sesquiterpene from Guarea macrophylla, Displays Potent and Selective Anthelmintic Activity against Angiostrongylus cantonensis. literature abstract metadata