Harungana
Harungana
Harungana is a plant traditionally found in Madagascar. While its use in traditional medicine has not been documented, scientific studies have shown promising results. Hexane and dichloromethane/methanol extracts of Harungana madagascariensis demonstrated antibacterial activity against multidrug-resistant Staphylococcus aureus and Pseudomonas aeruginosa, suggesting potential for enhancing antibiotic efficacy. Additionally, compounds from the plant showed promise as inhibitors of BfmR in Acinetobacter baumannii, though further validation is needed to confirm these findings. No significant safety concerns or drug interactions have been recorded, making it potentially safe for use, but its effectiveness and safety should be confirmed through additional research.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The hexane and dichloromethane/methanol extracts of Harungana madagascariensis showed antibacterial activity and modulated antibiotic resistance in multidrug-resistant Staphylococcus aureus.
- Harungana madagascariensis hosted more epiphyte and liana species than other native trees of similar age but not diameter.
- Harungana madagascariensis leaf extract showed significant antibacterial activity and enhanced antibiotic efficacy against multidrug-resistant Pseudomonas aeruginosa.
- The study identified harunganol-B and other compounds from Harungana madagascariensis as potential inhibitors of BfmR in Acinetobacter baumannii, warranting further validation.
Frequently asked questions
What is Harungana?
Harungana (Harungana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Harungana?
4 sourced findings are recorded for Harungana; the strongest carries evidence grade D. For example: The hexane and dichloromethane/methanol extracts of Harungana madagascariensis showed antibacterial activity and modulated antibiotic resistance in multidrug-resistant Staphylococcus aureus.
How strong is the evidence for Harungana?
The strongest finding for Harungana carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Harungana safe? What are the side effects?
No major safety issues are recorded for Harungana in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Harungana interact with medications?
No drug interactions are recorded for Harungana in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Harungana?
Harungana is also known as: Харонга.
Is Harungana a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Phytochemical Composition, Antibacterial Activity, Modes of Action, and Antibiotic Resistance-Modifying Effects of Harungana madagascariensis (Hypericaceae) Against Multidrug-Resistant Pseudomonas aeruginosa. literature abstract metadata
- T2 Anti-staphylococcal activity, antibiotic-resistance modulation effects and action of Harungana madagascariensis (Hypericaceae) fruit extracts on the antioxidant system of multidrug-resistant Staphylococcus aureus. literature abstract metadata
- T2 Harungana madagascariensis (Hypericaceae) is a key phorophyte for native epiphytes and lianas during ecological restoration: case study on an oceanic island. literature abstract metadata
- T2 Harunganol-B and beyond: unveiling nature's arsenal against drug-resistant Acinetobacter baumannii. literature abstract metadata