FolkKB

Harungana

Harungana

Harungana, specifically Harungana madagascariensis, is a plant native to Madagascar. Traditionally, there are no recorded uses of this plant in any known medical practices or traditions. Scientific evidence suggests that H. madagascariensis hosts a diverse array of epiphytes and lianas, indicating its ecological significance. Additionally, leaf extracts from the plant have shown significant antibacterial activity and enhanced antibiotic efficacy against multidrug-resistant Pseudomonas aeruginosa, with harunganol-B identified as a potential inhibitor of BfmR in Acinetobacter baumannii, though further validation is needed. The study also found that H. madagascariensis extracts exhibited antibacterial activity and modulated antibiotic resistance in multidrug-resistant Staphylococcus aureus. Safety concerns are currently minimal, with no major issues recorded, and there are no known drug interactions associated with the use of this plant.

At a glance
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The hexane and dichloromethane/methanol extracts of Harungana madagascariensis showed antibacterial activity and modulated antibiotic resistance in multidrug-resistant Staphylococcus aureus. D PMID
  • Harungana madagascariensis hosted more epiphyte and liana species than other native trees of similar age but not diameter. D PMID
  • Harungana madagascariensis leaf extract showed significant antibacterial activity and enhanced antibiotic efficacy against multidrug-resistant Pseudomonas aeruginosa. D PMID
  • The study identified harunganol-B and other compounds from Harungana madagascariensis as potential inhibitors of BfmR in Acinetobacter baumannii, warranting further validation. D PMID

Frequently asked questions

What is Harungana?

Harungana (Harungana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Harungana?

4 sourced findings are recorded for Harungana; the strongest carries evidence grade D. For example: The hexane and dichloromethane/methanol extracts of Harungana madagascariensis showed antibacterial activity and modulated antibiotic resistance in multidrug-resistant Staphylococcus aureus.

How strong is the evidence for Harungana?

The strongest finding for Harungana carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Harungana safe? What are the side effects?

No major safety issues are recorded for Harungana in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Harungana interact with medications?

No drug interactions are recorded for Harungana in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Harungana?

Harungana is also known as: Харонга.

Is Harungana a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Phytochemical Composition, Antibacterial Activity, Modes of Action, and Antibiotic Resistance-Modifying Effects of Harungana madagascariensis (Hypericaceae) Against Multidrug-Resistant Pseudomonas aeruginosa. literature abstract metadata
  2. T2 Anti-staphylococcal activity, antibiotic-resistance modulation effects and action of Harungana madagascariensis (Hypericaceae) fruit extracts on the antioxidant system of multidrug-resistant Staphylococcus aureus. literature abstract metadata
  3. T2 Harungana madagascariensis (Hypericaceae) is a key phorophyte for native epiphytes and lianas during ecological restoration: case study on an oceanic island. literature abstract metadata
  4. T2 Harunganol-B and beyond: unveiling nature's arsenal against drug-resistant Acinetobacter baumannii. literature abstract metadata