Horsfieldia irya
Horsfieldia irya
Horsfieldia irya is a plant native to Southeast Asia, particularly found in riparian vegetation. Traditional uses of this plant are not well-documented, and its medicinal applications have not been extensively studied within any known traditions. Scientific evidence suggests that compounds from H. irya, such as myristicyclins A and B isolated from related species, exhibit moderate cytotoxicity against cancer cell lines with selective toxicity towards cancer cells over normal ones. Additionally, a nutmeg hydroethanolic extract has shown significant antifungal activity, particularly against Fusarium culmorum, by targeting ergosterol biosynthesis. While the antimalarial potential of Horsfieldia species is promising, further research is needed to confirm these findings. No major safety issues or drug interactions have been recorded for this plant, but comprehensive studies are still required to fully understand its potential benefits and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Compound 13 from Horsfieldia irya showed moderate cytotoxicity against cancer cell lines with less activity against normal cells.
- The study found that a nutmeg extract showed significant activity against several phytopathogenic fungi, particularly Fusarium culmorum, through targeting ergosterol biosynthesis.
- After 34 years, 90 species of riparian plants were recorded across four streams near Tasik Kenyir.
- Myristicyclins A and B, isolated from Horsfieldia spicata, showed antimalarial activity against Plasmodium falciparum in vitro.
Frequently asked questions
What is Horsfieldia irya?
Horsfieldia irya (Horsfieldia irya) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Horsfieldia irya?
4 sourced findings are recorded for Horsfieldia irya; the strongest carries evidence grade D. For example: Compound 13 from Horsfieldia irya showed moderate cytotoxicity against cancer cell lines with less activity against normal cells.
How strong is the evidence for Horsfieldia irya?
The strongest finding for Horsfieldia irya carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Horsfieldia irya safe? What are the side effects?
No major safety issues are recorded for Horsfieldia irya in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Horsfieldia irya interact with medications?
No drug interactions are recorded for Horsfieldia irya in our sources. This does not rule them out — check with a pharmacist.
Is Horsfieldia irya a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Myristicyclins A and B: antimalarial procyanidins from Horsfieldia spicata from Papua New Guinea. literature abstract metadata
- T2 Species richness of riparian vegetation after three decades of Kenyir dam establishment. literature abstract metadata
- T2 Cytotoxicity of acylphloroglucinol derivatives from the fruits of Horsfieldia irya. literature abstract metadata
- T2 Phytoconstituents and Ergosterol Biosynthesis-Targeting Antimicrobial Activity of Nutmeg (Myristica fragans Houtt.) against Phytopathogens. literature abstract metadata