Black Henbane

Hyoscyamus niger

Hyoscyamus niger, commonly known as black henbane, is a traditional medicinal plant found in Europe, Asia, and North Africa. It has not been extensively used in traditional medicine practices, though it has historical significance due to its potent antispasmodic properties. Scientific evidence suggests that Hyoscyamus niger can be effective in reducing cough and shortness of breath when combined with propolis in hospitalized COVID-19 patients; however, the overall body of research is limited. Studies have also shown that blue LED light combined with 4 mg/L glycine leads to higher atropine accumulation, while red LED light with 8 mg/L glycine results in higher scopolamine levels in callus cultures of Hyoscyamus niger. Henbane poisoning, particularly in children, can present with antimuscarinic symptoms such as agitation and mydriasis; severe cases may include seizures and acute kidney injury. Safety concerns are minimal based on current data, but the plant is highly toxic due to its atropine and scopolamine content. There have been no recorded major issues or drug interactions reported in the literature, though use should be approached with extreme caution given its potent nature.

At a glance
Best evidence
B
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found that Hyoscyamus niger poisoning in a child could present with hyperactivity and euphoria without agitation. D PMID
  • Hyoscyamus niger L. extract combined with propolis significantly reduced cough, shortness of breath, and CRP levels compared to placebo in hospitalized COVID-19 patients. B PMID
  • The study found that using blue LED light and varying concentrations of glycine significantly increased the accumulation of atropine, scopolamine, and gallic acid in Hyoscyamus niger callus cultures. D PMID
  • Henbane poisoning in children can result in severe symptoms including seizures and acute kidney injury. D PMID

Frequently asked questions

What is Black Henbane?

Black Henbane (Hyoscyamus niger) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Black Henbane?

4 sourced findings are recorded for Black Henbane; the strongest carries evidence grade B. For example: The study found that Hyoscyamus niger poisoning in a child could present with hyperactivity and euphoria without agitation.

How strong is the evidence for Black Henbane?

The strongest finding for Black Henbane carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Black Henbane safe? What are the side effects?

No major safety issues are recorded for Black Henbane in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Black Henbane interact with medications?

No drug interactions are recorded for Black Henbane in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Black Henbane?

Black Henbane is also known as: Белена чёрная.

Is Black Henbane a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 The influence of propolis plus Hyoscyamus niger L. against COVID-19: A phase II, multicenter, placebo-controlled, randomized trial. literature abstract metadata
  2. T2 Enhancing the accumulation of scopolamine and atropine in Hyoscyamus niger L. callus by LED light and glycine-a cheap method. literature abstract metadata
  3. T2 The toxicity of hyoscyamus niger (henbane) in children: a five-year experience in a pediatric intensive care unit. literature abstract metadata
  4. T2 Hyperactivity and Euphoria Without Agitation Due to Hyoscyamus niger (Henbane) Poisoning in a Child. literature abstract metadata