Hypericum scabrum
Hypericum scabrum
Hypericum scabrum, a plant native to regions in Europe and Asia, has not been traditionally used for medicinal purposes. Scientific studies have shown promising results with its extracts. The methanolic extract of Hypericum scabrum demonstrated high antioxidant activity and non-toxicity, enhancing the antimicrobial properties of hydrogels. Additionally, the hydroalcoholic extract exhibited significant inhibitory effects on Leishmania major promastigotes, though less potent than the control drug glucantime. Research also indicated notable inhibitory activity against α-glucosidase and selective cytotoxicity against U87MG glioblastoma cells. The methanol extract showed significant collagenase inhibition and antioxidant effects without genotoxicity. To date, no major safety issues or drug interactions have been recorded for Hypericum scabrum, but further research is warranted to fully understand its potential applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The methanolic extract of Hypericum scabrum showed high antioxidant activity and non-toxicity, enhancing the hydrogel's antimicrobial properties.
- The hydroalcoholic extract of Hypericum scabrum showed significant inhibitory effect on Leishmania major promastigotes, though less potent than the control drug glucantime.
- The methanol extract of Hypericum scabrum showed notable inhibitory activity against α-glucosidase and exhibited selectivity towards glioblastoma cells in vitro.
- The study found that Hypericum scabrum extract demonstrated significant collagenase inhibition and antioxidant effects without genotoxicity.
Frequently asked questions
What is Hypericum scabrum?
Hypericum scabrum (Hypericum scabrum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Hypericum scabrum?
4 sourced findings are recorded for Hypericum scabrum; the strongest carries evidence grade D. For example: The methanolic extract of Hypericum scabrum showed high antioxidant activity and non-toxicity, enhancing the hydrogel's antimicrobial properties.
How strong is the evidence for Hypericum scabrum?
The strongest finding for Hypericum scabrum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Hypericum scabrum safe? What are the side effects?
No major safety issues are recorded for Hypericum scabrum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Hypericum scabrum interact with medications?
No drug interactions are recorded for Hypericum scabrum in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Hypericum scabrum?
Hypericum scabrum is also known as: Зверобой шероховатый.
Is Hypericum scabrum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Anti-leishmanial activity of Hypericum Scabrum extract against Leishmania major. literature abstract metadata
- T2 Morphological, anatomical, and bioactive properties of Hypericum scabrum L.: effects on diabetes mellitus, Alzheimer's disease, and HDFa fibroblasts and U87-MG cancer cells. literature abstract metadata
- T2 Hypericum scabrum L.-infused locust bean gum/agar hydrogel film: A novel candidate for anti-aging facial mask applications. literature abstract metadata
- T2 Investigating the effective features of chitosan alginate hydrogel wound dressing containing Hypericum scabrum plant extract. literature abstract metadata