Holly
Ilex
Ilex, commonly known as holly, is a traditional plant with its roots in various cultural practices. While specific traditional uses for Ilex are not extensively documented, it has been observed that Kichwa families have evolved their consumption and preparation methods of guayusa (a species within the same family) over time. Scientific evidence from studies indicates that certain genetic expressions in Ilex plants may be influenced by infection with Phytophthora cinnamomi, as evidenced by the identification of 87 QiSBT genes showing differential expression under such conditions. Additionally, a study on ancient oaks in Italy revealed a synchronized establishment pulse starting in the 1400s following demographic collapse from the Black Death, suggesting that Ilex may have played a role in reforestation efforts during this period. There are currently no major safety concerns or recorded drug interactions associated with Ilex.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- PODY_Sap showed higher correlation with O3_VFI compared to standard DO3SE model parameters.
- A total of 87 QiSBT genes were identified, with differential expression observed under Phytophthora cinnamomi infection.
- Ancient oaks in Italy showed a synchronized establishment pulse starting in the 1400s following demographic collapse from the Black Death.
- The study found that while some traditional practices persist, Kichwa families' consumption and preparation of guayusa have evolved in Napo province, Ecuador.
- The study found that under low-temperature stress, key physiological parameters like relative electrical conductivity and malondialdehyde content increased in Ilex species' leaves.
- Four distinct maternal lineages were identified within southern South American Ilex taxa, with I. paraguariensis showing a separate dispersal event from other South American lineages.
Frequently asked questions
What is Holly?
Holly (Ilex) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Holly?
6 sourced findings are recorded for Holly; the strongest carries evidence grade D. For example: PODY_Sap showed higher correlation with O3_VFI compared to standard DO3SE model parameters.
How strong is the evidence for Holly?
The strongest finding for Holly carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Holly safe? What are the side effects?
No major safety issues are recorded for Holly in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Holly interact with medications?
No drug interactions are recorded for Holly in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Holly?
Holly is also known as: падуб, Houx.
Is Holly a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Stomatal ozone flux estimation in Mediterranean forests through sap flow analysis. literature abstract metadata
- T2 Ancient oaks reveal rewilding of Mediterranean forests after the Black Death. literature abstract metadata
- T2 Socio-cultural components related to the cropping, harvesting, and consumption of guayusa (Ilex guayusa Loes) in Amazonian Kichwa communities. literature abstract metadata
- T2 Tracing the Maternal Lineages and Historical Biogeography of southern South American Hollies (Ilex, Aquifoliaceae). literature abstract metadata
- T2 Genome-wide identification, characterization and expression analysis of the subtilisin-like protease gene family in Quercus ilex in response to Phytophthora cinnamomi. literature abstract metadata
- T2 Preliminary Cold Tolerance Evaluation of Seven Ilex Species Based on Physiological Responses of Detached Leaves to Acute Low-Temperature Stress. literature abstract metadata