Kleinhovia
Kleinhovia
Kleinhovia is a plant traditionally used in various herbal practices, though specific uses are not well-documented. Scientific studies have shown that extracts from Kleinhovia hospita exhibit significant antiplasmodial activity against P. falciparum, the parasite responsible for malaria. Additionally, compounds isolated from Kleinhovia hospita, such as kleinhospitine A, β-amyrin, and castiliferol, have shown potential as cathepsin L inhibitors with lower binding energies than schinol. These extracts also demonstrated in vitro antibacterial activity against Staphylococcus aureus without affecting fibroblast toxicity or proliferation. While the study isolated and characterized several compounds from Kleinhovia hospita, including new cycloartane triterpenoids, no significant health effects were found. Safety records indicate that there are no major issues recorded for this plant, and it has not been reported to interact with any drugs as of current research findings.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Seven extracts, including one from Kleinhovia hospita, showed significant antiplasmodial activity against P. falciparum.
- Kleinhovia hospita compounds kleinhospitine A, β-amyrin, and castiliferol showed potential as cathepsin L inhibitors with lower binding energies than schinol.
- The study identified several new cycloartane triterpenoids from Kleinhovia hospita with varying structures and biological activities.
- Kleinhovia hospita extracts showed in vitro antibacterial activity against Staphylococcus aureus with no toxicity to human dermal fibroblasts.
Frequently asked questions
What is Kleinhovia?
Kleinhovia (Kleinhovia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kleinhovia?
4 sourced findings are recorded for Kleinhovia; the strongest carries evidence grade D. For example: Seven extracts, including one from Kleinhovia hospita, showed significant antiplasmodial activity against P. falciparum.
How strong is the evidence for Kleinhovia?
The strongest finding for Kleinhovia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Kleinhovia safe? What are the side effects?
No major safety issues are recorded for Kleinhovia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kleinhovia interact with medications?
No drug interactions are recorded for Kleinhovia in our sources. This does not rule them out — check with a pharmacist.
Is Kleinhovia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Kleinhospitine E and Cycloartane Triterpenoids from Kleinhovia hospita. literature abstract metadata
- T2 In vitro antibacterial activity of extracts from Samoan medicinal plants and their effect on proliferation and migration of human fibroblasts. literature abstract metadata
- T2 Molecular modeling for potential cathepsin L inhibitor identification as new anti-photoaging agents from tropical medicinal plants. literature abstract metadata
- T2 Evaluation of the antiplasmodial and anti-Toxoplasma activities of several Indonesian medicinal plant extracts. literature abstract metadata