Kopsia arborea
Kopsia arborea
Kopsia arborea is a plant traditionally not used in any known medical practices. Scientific research has identified several new alkaloids from Kopsia arborea, which have shown varying levels of inhibition against cyclin-dependent kinase 5 and tau phosphorylation, though the evidence is still preliminary and more studies are needed to confirm these findings. The plant also contains two new monoterpenoid indole alkaloids with cytotoxicity assessed in vitro, demonstrating growth inhibitory activity against HT-29 cells and significant cytotoxic activity against six human lung cancer cell lines. Safety concerns for Kopsia arborea do not appear to be major, but no extensive safety studies have been conducted. Similarly, there is currently no recorded information on potential drug interactions with the plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Three new alkaloids from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation, though effects vary in potency.
- Two new monoterpenoid indole alkaloids were identified from Kopsia arborea kernels along with known alkaloids, but no significant health effects are reported.
- Three new alkaloids were isolated from Kopsia arborea, including one with a unique carbon-nitrogen skeleton and two incorporating a tetrahydrofuranone ring, showing in vitro growth inhibitory activity against HT-29 cells.
- Three new monoterpenoid indole alkaloids were isolated from Kopsia arborea, showing significant cytotoxic activity against six human lung cancer cell lines.
Frequently asked questions
What is Kopsia arborea?
Kopsia arborea (Kopsia arborea) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kopsia arborea?
4 sourced findings are recorded for Kopsia arborea; the strongest carries evidence grade D. For example: Three new alkaloids from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation, though effects vary in potency.
How strong is the evidence for Kopsia arborea?
The strongest finding for Kopsia arborea carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Kopsia arborea safe? What are the side effects?
No major safety issues are recorded for Kopsia arborea in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kopsia arborea interact with medications?
No drug interactions are recorded for Kopsia arborea in our sources. This does not rule them out — check with a pharmacist.
Is Kopsia arborea a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 A Cytotoxic Indole Characterized by Incorporation of a Unique Carbon-Nitrogen Skeleton and Two Pentacyclic Corynanthean Alkaloids Incorporating a Substituted Tetrahydrofuranone Ring from Kopsia arborea. literature abstract metadata
- T2 Cytotoxic monoterpenoid indole alkaloids from the aerial part of Kopsia arborea. literature abstract metadata
- T2 Two new monoterpenoid indole alkaloids from the kernels of Kopsia arborea. literature abstract metadata
- T2 Monoterpenoid indole alkaloid dimers from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation. literature abstract metadata