Bugleweed
Lycopus virginicus
Lycopus virginicus, commonly known as American bugleweed or Virginia bugleweed, is a traditional herbal remedy that originates from North America. While its use in specific traditional medicine practices has not been extensively documented, studies have shown potential for its medicinal properties. Scientific research indicates that extracts of Lycopus virginicus can inhibit the binding and biological activity of Graves' immunoglobulins, suggesting possible benefits for conditions associated with thyroid function. Additionally, it has demonstrated inhibition of iodothyronine deiodinase activities in rat liver microsomes, which could have implications for thyroid hormone metabolism. However, the strength of these findings is currently limited by the scope and depth of available research. No major safety concerns or reported drug interactions have been recorded to date, but further investigation is warranted to fully understand its potential benefits and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Flavone glucuronides of apigenin, acacetin, luteolin, and their methyl ester were isolated from Lycopus virginicus, with varying concentrations found in related species.
- Freeze-dried extracts and auto-oxidized constituents of Lycopus virginicus inhibited the binding and biological activity of Graves' immunoglobulins in a dose-dependent manner.
- Lycopus virginicus extracts inhibited the binding of bovine thyrotropin to human thyroid membranes in a dose-related manner.
- Lycopus virginicus extracts inhibit iodothyronine deiodinase activities in rat liver microsomes, varying by plant species and extraction method.
Frequently asked questions
What is Bugleweed?
Bugleweed (Lycopus virginicus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bugleweed?
4 sourced findings are recorded for Bugleweed; the strongest carries evidence grade D. For example: Flavone glucuronides of apigenin, acacetin, luteolin, and their methyl ester were isolated from Lycopus virginicus, with varying concentrations found in related species.
How strong is the evidence for Bugleweed?
The strongest finding for Bugleweed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bugleweed safe? What are the side effects?
No major safety issues are recorded for Bugleweed in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bugleweed interact with medications?
No drug interactions are recorded for Bugleweed in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bugleweed?
Bugleweed is also known as: Зюзник виргинский.
Is Bugleweed a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Flavone glucuronides of Lycopus virginicus. literature abstract metadata
- T2 Extracts and auto-oxidized constituents of certain plants inhibit the receptor-binding and the biological activity of Graves' immunoglobulins. literature abstract metadata
- T2 Antihormonal effects of plant extracts: iodothyronine deiodinase of rat liver is inhibited by extracts and secondary metabolites of plants. literature abstract metadata
- T2 Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. literature abstract metadata