Common Hoarhound
Marrubium vulgare
Marrubium vulgare, commonly known as white horehound, originates from traditional medicine practices in Europe and parts of Asia. It has been traditionally used for various purposes such as treating respiratory issues and digestive problems, though specific uses vary across different cultures. Scientific evidence suggests that water extracts from both cultivated and wild-growing Marrubium vulgare exhibit selective antiproliferative effects against certain cancer cell lines, indicating potential anticancer activity. Computational studies have also identified thymol-Leu-Trp-phosphinic acid as a possible LasB inhibitor; however, experimental validation is required to confirm these findings. No major safety concerns or drug interactions have been recorded for Marrubium vulgare, though further research is needed to fully understand its potential benefits and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Water extracts from leaves and flowers of both in vitro cultivated and wild-growing Marrubium vulgare showed selective antiproliferative effects against cancer cell lines.
- This study identified two compounds from Marrubium vulgare that potentially interact with Hsp90, suggesting its use as an anticancer scaffold.
- The study found that Marrubium vulgare leaf extracts could effectively adsorb and photodegrade crystal violet from wastewater.
- Computational screening identified thymol-Leu-Trp-phosphinic acid as a potential selective LasB inhibitor with predicted binding affinity comparable to a reference inhibitor.
Frequently asked questions
What is Common Hoarhound?
Common Hoarhound (Marrubium vulgare) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Common Hoarhound?
4 sourced findings are recorded for Common Hoarhound; the strongest carries evidence grade D. For example: Water extracts from leaves and flowers of both in vitro cultivated and wild-growing Marrubium vulgare showed selective antiproliferative effects against cancer cell lines.
How strong is the evidence for Common Hoarhound?
The strongest finding for Common Hoarhound carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Common Hoarhound safe? What are the side effects?
No major safety issues are recorded for Common Hoarhound in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Common Hoarhound interact with medications?
No drug interactions are recorded for Common Hoarhound in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Common Hoarhound?
Common Hoarhound is also known as: Шандра обыкновенная, Marrube blanc.
Is Common Hoarhound a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Phytochemical Profiling and Structure-Based Computational Characterization of Marrubium vulgare L. Compounds as Hsp90 Modulators. literature abstract metadata
- T2 Antioxidant and Anticancer Activities of Water Extracts from Flowers, Leaves and Stems of In Vitro Cultivated and Wild-Growing Marrubium vulgare Plants. literature abstract metadata
- T2 Rational Design and Virtual Screening of Antimicrobial Terpene-Based Leads from Marrubium vulgare Essential Oil: Structure-Based Optimization for Food Preservation and Safety Applications. literature abstract metadata
- T2 Marrubium vulgare Leaves as a Biosorbent and Reducing Agent for the Green Synthesis of ZnO and Ag/ZnO: Towards an Efficient Treatment of Colored Wastewater. literature abstract metadata