Bead Tree
Melia azedarach
Melia azedarach, commonly known as chinaberry or bead tree, is a traditional plant used in various cultural practices but lacks specific documented uses. Scientific studies have shown that extracts from this plant exhibit significant ovicidal and larvicidal activity against Culex pipiens mosquitoes at a 1% concentration. Additionally, compounds isolated from its fruits demonstrated larvicidal effects on Aedes aegypti larvae, possibly through oxidative imbalance and midgut damage. The bark of Melia azedarach yielded seven limonoids, one of which, Isotoosendanin, showed potent anti-hepatocarcinoma activity both in vitro and in vivo. Furthermore, biopesticides based on this plant were effective against Aspergillus niger mycelial growth and reduced storage rot incidence in garlic. No major safety concerns or recorded drug interactions have been noted for Melia azedarach to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Melia azedarach extracts showed significant ovicidal and larvicidal activity against Culex pipiens with 1% (w/v) concentration.
- Seven limonoids were isolated from Melia azedarach bark, with one (ITSN) showing potent anti-hepatocarcinoma activity both in vitro and in vivo.
- Melia azedarach-based biopesticides showed significant inhibition of Aspergillus niger mycelial growth in vitro and storage studies.
- The study found that 17-epi-melianodiol, from Melia azedarach fruits, showed larvicidal activity against Aedes aegypti larvae, associated with oxidative imbalance and midgut damage.
Frequently asked questions
What is Bead Tree?
Bead Tree (Melia azedarach) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bead Tree?
4 sourced findings are recorded for Bead Tree; the strongest carries evidence grade D. For example: Melia azedarach extracts showed significant ovicidal and larvicidal activity against Culex pipiens with 1% (w/v) concentration.
How strong is the evidence for Bead Tree?
The strongest finding for Bead Tree carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bead Tree safe? What are the side effects?
No major safety issues are recorded for Bead Tree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bead Tree interact with medications?
No drug interactions are recorded for Bead Tree in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bead Tree?
Bead Tree is also known as: Мелия азедарах.
Is Bead Tree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 An ecofriendly approach for management of storage rot disease of garlic caused by Aspergillus niger. literature abstract metadata
- T2 Anti-Hepatocarcinoma Activity and Mechanism of Isosendanin and Its Novel Structural Analogues Isolated from the Bark of Melia azedarach L.: In Vitro and In Vivo Studies. literature abstract metadata
- T2 17-epi-Melianodiol, a new protolimonoid from Melia azedarach fruits, exhibits larvicidal activity and is associated with oxidative imbalance and midgut epithelial damage in Aedes aegypti larvae. literature abstract metadata
- T2 Chemical Composition and Control Potential of Melia azedarach Extracts Against Culex pipiens. literature abstract metadata