Papaver somniferum
Papaver somniferum
Papaver somniferum, commonly known as opium poppy, originates from traditional medicine practices in various cultures. It has been traditionally used for its analgesic and sedative properties, though specific uses vary widely across different traditions. Scientific evidence indicates moderate activity of benzylisoquinoline alkaloids (BIAs) from Papaver somniferum against multidrug-resistant Klebsiella pneumoniae, with a zone of inhibition of 11 ± 0.23 mm. Morphine, papaverine, noscapine, and nicotine were identified in analyzed samples, along with mendipite. The study also highlights specific chemical groups in buprenorphine contributing to its binding affinity and partial agonist activity, providing insights into its mechanism of action. No major safety issues or drug interactions have been recorded for Papaver somniferum based on current data.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study reviewed benzylisoquinoline alkaloids (BIAs) from various plants, including Papaver somniferum, highlighting their diverse bioactivities.
- Papaver somniferum showed moderate activity against multidrug-resistant Klebsiella pneumoniae with a zone of inhibition of 11 ± 0.23 mm.
- The study identifies specific chemical groups in buprenorphine contributing to its binding affinity and partial agonist activity at μ-opioid receptors.
- Morphine, papaverine, noscapine, and nicotine were identified in the analyzed tablets, while one sample also contained lead oxychloride.
Frequently asked questions
What is Papaver somniferum?
Papaver somniferum (Papaver somniferum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Papaver somniferum?
4 sourced findings are recorded for Papaver somniferum; the strongest carries evidence grade D. For example: The study reviewed benzylisoquinoline alkaloids (BIAs) from various plants, including Papaver somniferum, highlighting their diverse bioactivities.
How strong is the evidence for Papaver somniferum?
The strongest finding for Papaver somniferum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Papaver somniferum safe? What are the side effects?
No major safety issues are recorded for Papaver somniferum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Papaver somniferum interact with medications?
No drug interactions are recorded for Papaver somniferum in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Papaver somniferum?
Papaver somniferum is also known as: Мак снотворный, pavot somnifère.
Is Papaver somniferum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Pharmacological evaluation of selected medicinal plant extracts against multidrug-resistant Klebsiella pneumoniae: implications for inflammation-associated respiratory infections. literature abstract metadata
- T2 Emerging Insights into the Distinct Pharmacological Mechanisms of Buprenorphine. literature abstract metadata
- T2 [Chemical forensic analysis of medicinal tablets discovered during excavations of an ancient burial]. literature abstract metadata
- T2 Systematic review of naturally occurring benzylisoquinoline alkaloids (2015-2024): phytochemistry, bioactivity and structure-activity relationship. literature abstract metadata