Korean paulownia
Paulownia coreana
Paulownia coreana, a tree native to East Asia, has garnered attention for its potential medicinal properties. Traditionally, there are no recorded uses of this plant in any known medical practices. Scientific studies have shown that isocampneoside II from the seeds of Paulownia coreana exhibits aldose reductase inhibition with an IC50 value of 9.72 µM, and compounds identified from its chloroplast genome show potential for inhibiting nitric oxide production. Additionally, PCAC (a compound derived from Paulownia coreana) has demonstrated antiproliferative activity against breast and cervical cancer cells through both extrinsic and intrinsic apoptotic pathways. While no major safety concerns or drug interactions have been recorded, further research is necessary to fully understand its efficacy and potential applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Isocampneoside II from Paulownia coreana seeds inhibited aldose reductase with an IC50 value of 9.72 µM.
- The chloroplast genomes of Paulownia coreana and P. tomentosa were sequenced and found to be similar in structure to other angiosperms.
- The study identified several compounds from Paulownia coreana that showed potential inhibition of nitric oxide production.
- PCAC from Paulownia coreana shows antiproliferative activity against breast and cervical cancer cells through both extrinsic and intrinsic apoptotic pathways.
Frequently asked questions
What is Korean paulownia?
Korean paulownia (Paulownia coreana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Korean paulownia?
4 sourced findings are recorded for Korean paulownia; the strongest carries evidence grade D. For example: Isocampneoside II from Paulownia coreana seeds inhibited aldose reductase with an IC50 value of 9.72 µM.
How strong is the evidence for Korean paulownia?
The strongest finding for Korean paulownia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Korean paulownia safe? What are the side effects?
No major safety issues are recorded for Korean paulownia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Korean paulownia interact with medications?
No drug interactions are recorded for Korean paulownia in our sources. This does not rule them out — check with a pharmacist.
Is Korean paulownia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Inhibition of aldose reductase by phenylethanoid glycoside isolated from the seeds of Paulownia coreana. literature abstract metadata
- T2 Inhibitory effect and mechanism on antiproliferation of isoatriplicolide tiglate (PCAC) from Paulownia Coreana. literature abstract metadata
- T2 Geranylated flavanones from Paulownia coreana and their inhibitory effects on nitric oxide production. literature abstract metadata
- T2 Two complete chloroplast genome sequences of genus Paulownia (Paulowniaceae): Paulownia coreana and P. tomentosa. literature abstract metadata