Pergularia

Pergularia

Pergularia is a genus of plants with traditional uses not well-documented. Studies have shown that biogenically synthesized gold nanoparticles from Pergularia daemia leaves exhibit significant antiproliferative effects against nasopharyngeal carcinoma cells in vitro, suggesting potential anticancer properties. Additionally, Pergularia tomentosa essential oil demonstrates strong antimicrobial and anti-inflammatory activities, while Pergularia daemia also shows notable antioxidant and antibacterial activity. Zinc oxide nanoparticles synthesized from Pergularia daemia fibre exhibit strong antibacterial and antibiofilm activity against dental pathogens. To date, no major safety issues or drug interactions have been recorded for these plants.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found that biogenically synthesized gold nanoparticles from Pergularia daemia leaves showed significant antiproliferative effects against nasopharyngeal carcinoma cells in vitro. D PMID
  • Pergularia daemia showed stronger antioxidant and antibacterial activity, while Cynanchum viminale exhibited greater cytotoxicity against cancer cell lines. D PMID
  • Pergularia tomentosa essential oil showed strong antimicrobial activity and significant anti-inflammatory effects. D PMID
  • Pergularia daemia-derived zinc oxide nanoparticles exhibit strong antibacterial and antibiofilm activity, showing potential for dental and biomedical applications. D PMID

Frequently asked questions

What is Pergularia?

Pergularia (Pergularia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Pergularia?

4 sourced findings are recorded for Pergularia; the strongest carries evidence grade D. For example: The study found that biogenically synthesized gold nanoparticles from Pergularia daemia leaves showed significant antiproliferative effects against nasopharyngeal carcinoma cells in vitro.

How strong is the evidence for Pergularia?

The strongest finding for Pergularia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Pergularia safe? What are the side effects?

No major safety issues are recorded for Pergularia in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Pergularia interact with medications?

No drug interactions are recorded for Pergularia in our sources. This does not rule them out — check with a pharmacist.

Is Pergularia a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 GC-MS Analysis of Pergularia tomentosa Essential Oil: Determination of Antibacterial, Antifungal, and Anti-Inflammatory Activities. literature abstract metadata
  2. T2 A comparative analysis of bioactive phytochemicals in Cynanchum viminale (L.) L. and Pergularia daemia (Forssk.) Chiov. from Saudi Arabian folk medicine. literature abstract metadata
  3. T2 Synthesis of ZnO Nanoparticles From Pergularia daemia Fibre: Potential for Caries Prevention and Infection Control. literature abstract metadata
  4. T2 Biogenic gold nanoparticles synthesized from Pergularia daemia leaves: a novel approach for nasopharyngeal carcinoma therapy. literature abstract metadata