Marshpepper knotweed
Persicaria hydropiper
Persicaria hydropiper, commonly known as water pepper, is a plant traditionally used in some Asian and European cuisines but lacks specific traditional medicinal uses. Scientific evidence suggests that it may have potential benefits against Alzheimer's disease markers, with studies indicating its ability to reduce oxidative stress and inhibit amyloid-β/tau fibrillation. The volatile oil profile of Persicaria hydropiper has been characterized, revealing the presence of eighteen sesquiterpenes, with drimenol being the most abundant component. Additionally, it has shown potential in environmental remediation by effectively removing acephate from contaminated soil when combined with Enterobacter badius. MicroRNA and natural compounds from Persicaria hydropiper have also been identified as having possible interactions with KDR (VEGFR-2), though further research is needed to confirm these findings. No major safety concerns or known drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Persicaria hydropiper showed protective effects against Alzheimer's disease markers in SH-SY5Y cells by reducing oxidative stress and amyloid-β/tau fibrillation.
- The study characterized the volatile oil profile of water pepper, identifying it as rich in sesquiterpenes, particularly drimane-type compounds.
- The study found that combining Bacillus badius and Persicaria hydropiper achieved high removal rates of acephate in contaminated soil.
- This study identified one microRNA and two natural compounds from Persicaria hydropiper that showed potential interaction with KDR, the gene encoding VEGFR-2.
Frequently asked questions
What is Marshpepper knotweed?
Marshpepper knotweed (Persicaria hydropiper) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Marshpepper knotweed?
4 sourced findings are recorded for Marshpepper knotweed; the strongest carries evidence grade D. For example: Persicaria hydropiper showed protective effects against Alzheimer's disease markers in SH-SY5Y cells by reducing oxidative stress and amyloid-β/tau fibrillation.
How strong is the evidence for Marshpepper knotweed?
The strongest finding for Marshpepper knotweed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Marshpepper knotweed safe? What are the side effects?
No major safety issues are recorded for Marshpepper knotweed in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Marshpepper knotweed interact with medications?
No drug interactions are recorded for Marshpepper knotweed in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Marshpepper knotweed?
Marshpepper knotweed is also known as: Горец перечный.
Is Marshpepper knotweed a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Computational analysis of miRNA mediated KDR gene regulation and natural VEGFR2 inhibitors from Persicaria hydropiper in hepatocellular carcinoma. literature abstract metadata
- T2 Isolation of acephate-degrading bacteria and phytoremediation-microbial remediation from soil for the project of water diversion from the Yangtze River to Chaohu Lake. literature abstract metadata
- T2 Persicaria hydropiper attenuates oxidative stress and reactive oxygen species, and inhibits amyloid-β/tau in SH-SY5Y cell lines via multiple pathways of Alzheimer's disease. literature abstract metadata
- T2 Drimane Sesquiterpene-Rich Volatile Oil Profile of Water Pepper (Persicaria hydropiper), a Widely Distributed Spicy Herb. literature abstract metadata