Corktree
Phellodendron
Phellodendron is a traditional Chinese medicine plant native to northeastern China. Traditionally, it has not been extensively used for medicinal purposes in specific documented practices. Scientifically, Phellodendron amurense leaf extract shows potential as an antiviral by targeting early stages of viral infection, though the evidence remains preliminary and more research is needed. Studies have also identified genes and transcription factors involved in the biosynthesis of berberine between leaves and stems of Phellodendron amurense plantlets, which may be relevant to its medicinal properties. Clinical studies suggest elevated BLT1 expression in rheumatoid arthritis (RA) neutrophils, associated with impaired apoptosis and inflammation. To date, no major safety issues or drug interactions have been recorded for Phellodendron.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study developed prediction models for tree height and height to crown base using TLS data, improving accuracy through the inclusion of multiple ecological factors.
- Phellodendron amurense leaf extract shows antiviral activity by targeting early stages of viral infection, reducing infectivity in a dose-dependent manner.
- The study identified genes and transcription factors involved in the differential biosynthesis of berberine between leaves and stems of Phellodendron amurense.
- Clinical studies indicate elevated BLT1 expression in RA neutrophils, associated with impaired apoptosis and inflammation.
Frequently asked questions
What is Corktree?
Corktree (Phellodendron) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Corktree?
4 sourced findings are recorded for Corktree; the strongest carries evidence grade D. For example: The study developed prediction models for tree height and height to crown base using TLS data, improving accuracy through the inclusion of multiple ecological factors.
How strong is the evidence for Corktree?
The strongest finding for Corktree carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Corktree safe? What are the side effects?
No major safety issues are recorded for Corktree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Corktree interact with medications?
No drug interactions are recorded for Corktree in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Corktree?
Corktree is also known as: Бархат.
Is Corktree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Integrated Transcriptome and Metabolome Analysis Reveals Differential Berberine Biosynthesis in Leaves and Stems of Phellodendron amurense Rupr. Plantlets. literature abstract metadata
- T2 Phellodendron amurense Leaf Extract Inhibits Rhabdovirus Infection by Targeting Early Stages of Viral Entry. literature abstract metadata
- T2 [Prediction models for tree height and height to crown base of individual trees in valuable hardwood broad-leaved forests of Northeast China based on terrestrial laser scanning data]. literature abstract metadata
- T2 Therapeutic Potential of Phellodendrine/ Atractylenolide-I Combination in Rheumatoid Arthritis: Targeting Neutrophil Apoptosis Through LTB4/BLT1 Pathway Suppression. literature abstract metadata