dragon-of-the-world
Phyllanthus pulcher
Phyllanthus pulcher is a plant traditionally not known for any specific medicinal uses. Scientific evidence suggests that its aerial parts, particularly when used as a DCM extract, may exhibit significant anticancer activity against certain prostate cancer cell lines. Additionally, salicylic acid from the plant's hairy roots has been found to increase phenol and phenylpropanoid derivatives, which could have potential biological activities. The plant also showed moderate anti-angiogenic activity in assays but with lower cytotoxicity towards cancer cells. Two compounds identified from Sphingomonas sanguinis DM associated with Phyllanthus pulcher demonstrated moderate antimicrobial and cytotoxic activities. No major safety concerns or known drug interactions have been recorded for this plant, though further research is needed to fully understand its potential applications and effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The DCM extract of Phyllanthus pulcher aerial parts showed significant anticancer activity against DU-145 prostate cancer cell lines.
- The study found that salicylic acid 50 μM significantly increased phenol and phenylpropanoid derivatives in Phyllanthus acuminatus hairy roots.
- The study identified two compounds from Sphingomonas sanguinis DM with moderate antimicrobial and cytotoxic activities.
- Phyllanthus pulcher, among other plants, showed moderate anti-angiogenic activity in the rat aortic ring assay.
Frequently asked questions
What is dragon-of-the-world?
dragon-of-the-world (Phyllanthus pulcher) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about dragon-of-the-world?
4 sourced findings are recorded for dragon-of-the-world; the strongest carries evidence grade D. For example: The DCM extract of Phyllanthus pulcher aerial parts showed significant anticancer activity against DU-145 prostate cancer cell lines.
How strong is the evidence for dragon-of-the-world?
The strongest finding for dragon-of-the-world carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is dragon-of-the-world safe? What are the side effects?
No major safety issues are recorded for dragon-of-the-world in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does dragon-of-the-world interact with medications?
No drug interactions are recorded for dragon-of-the-world in our sources. This does not rule them out — check with a pharmacist.
Is dragon-of-the-world a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Anti-angiogenic and cytotoxicity studies of some medicinal plants. literature abstract metadata
- T2 Anticancer properties and phenolic contents of sequentially prepared extracts from different parts of selected medicinal plants indigenous to Malaysia. literature abstract metadata
- T2 Evaluation of Salicylic Acid and Methyl Jasmonate as Elicitors in Phyllanthus acuminatus Hairy Roots by Non-Targeted Analysis Using High-Resolution Mass Spectrometry. literature abstract metadata
- T2 Phytochemical and biological assessment of secondary metabolites isolated from a rhizosphere strain, Sphingomonas sanguinis DM of Datura metel. literature abstract metadata