Pithecellobium dulce
Pithecellobium dulce
Pithecellobium dulce is a plant traditionally found in tropical regions of Central and South America. While its use in traditional medicine has not been extensively documented, it has shown promise in various scientific studies. Research indicates that extracts from Pithecellobium dulce may improve stress-induced behavioral deficits in zebrafish larvae without causing observable toxicity; however, the underlying mechanisms require further investigation. Additionally, this plant was noted for its inclusion in the diet of grazing cows during scarcity periods, suggesting potential nutritional benefits. Laboratory studies have identified oleanolic acid as a potential modulator of AKT1 and rutin as a potential modulator of AKT2, while also demonstrating antioxidant, wound-healing, and cytotoxic activities against cancer cell lines in vitro. No major safety concerns or known drug interactions have been recorded for Pithecellobium dulce.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Pithecellobium dulce extract improved stress-induced behavioral deficits in zebrafish larvae without toxicity, showing potential antioxidant and neuroplasticity-modulating effects.
- This study identified oleanolic acid as a potential selective modulator of AKT1 and rutin as a potential modulator of AKT2 from Pithecellobium dulce.
- Pithecellobium dulce extract showed antioxidant, wound-healing, and cytotoxic activities against cancer cell lines in vitro.
- Pithecellobium dulce was among the woody species found in the diet of grazing cows, contributing to their nutritional requirements during scarcity periods.
Frequently asked questions
What is Pithecellobium dulce?
Pithecellobium dulce (Pithecellobium dulce) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pithecellobium dulce?
4 sourced findings are recorded for Pithecellobium dulce; the strongest carries evidence grade D. For example: Pithecellobium dulce extract improved stress-induced behavioral deficits in zebrafish larvae without toxicity, showing potential antioxidant and neuroplasticity-modulating effects.
How strong is the evidence for Pithecellobium dulce?
The strongest finding for Pithecellobium dulce carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pithecellobium dulce safe? What are the side effects?
No major safety issues are recorded for Pithecellobium dulce in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pithecellobium dulce interact with medications?
No drug interactions are recorded for Pithecellobium dulce in our sources. This does not rule them out — check with a pharmacist.
Is Pithecellobium dulce a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Isolation and quantification of polyphenolics, exploration of antioxidant, cytotoxicity, and wound healing activities of Pithecellobium dulce (Roxb.) Benth. literature abstract metadata
- T2 Pharmacogenomic and in silico identification of isoform-selective AKT inhibitors from Pithecellobium dulce for precision cancer therapy. literature abstract metadata
- T2 The Botanical Composition of the Diet of Grazing Cows During the Dry Season in a Subtropical Region of Mexico. literature abstract metadata
- T2 Antidepressant-Like Effects of Pithecellobium dulce Fruit Extract in a Chronic Unpredictable Stress-Induced Zebrafish Larvae Model: Behavioral, Molecular, and Phytochemical Insights. literature abstract metadata