Pluchea lanceolata
Pluchea lanceolata
Pluchea lanceolata, a plant traditionally not known for specific medicinal uses, has shown some potential in various scientific studies. Research indicates that extracts from this plant, including NEM, Aflapin, and E-OA-7, may help manage symptoms of knee osteoarthritis, though the evidence is moderate. Additionally, Pluchea lanceolata demonstrated moderate antioxidant properties comparable to a reference standard, BHA, and showed moderate renal protective effects against esomeprazole-induced nephrotoxicity in rats, although coenzyme Q10 provided stronger protection. Notably, neolupenol from this plant was identified as a potential neuroprotective compound through modulation of the Keap1-Nrf2 axis, though further validation is required. No major safety concerns or recorded drug interactions have been noted for Pluchea lanceolata.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that NEM, Aflapin, and E-OA-7 supplements showed some effectiveness in managing knee osteoarthritis symptoms.
- The study identified neolupenol from Pluchea lanceolata as a potential neuroprotective compound through modulation of the Keap1-Nrf2 pathway, though further in vivo validation is needed.
- Pluchea lanceolata showed moderate renal protective effects against esomeprazole-induced nephrotoxicity in rats, alongside coenzyme Q10 providing stronger protection.
- The study developed an efficient tissue culture protocol for Pluchea lanceolata, leading to similar genome sizes and enhanced triterpenoid production in vitro compared to field-grown plants.
- Pluchea lanceolata showed moderate antioxidant potential in DPPH radical scavenging and reducing assays, comparable to the reference standard BHA.
Frequently asked questions
What is Pluchea lanceolata?
Pluchea lanceolata (Pluchea lanceolata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pluchea lanceolata?
5 sourced findings are recorded for Pluchea lanceolata; the strongest carries evidence grade A. For example: The study found that NEM, Aflapin, and E-OA-7 supplements showed some effectiveness in managing knee osteoarthritis symptoms.
How strong is the evidence for Pluchea lanceolata?
The strongest finding for Pluchea lanceolata carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Pluchea lanceolata safe? What are the side effects?
No major safety issues are recorded for Pluchea lanceolata in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pluchea lanceolata interact with medications?
No drug interactions are recorded for Pluchea lanceolata in our sources. This does not rule them out — check with a pharmacist.
Is Pluchea lanceolata a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Native wild plants in Karachi, Pakistan: Rich source of antioxidant raw material. literature abstract metadata
- T2 Genome size and gas chromatography-mass spectrometry (GC-MS) analysis of field-grown and in vitro regenerated Pluchea lanceolata plants. literature abstract metadata
- T2 Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis. literature abstract metadata
- T2 Therapeutic Potential of products derived from Pluchea lanceolata for Alzheimer's Disease Treatment. literature abstract metadata
- T2 Protective effects of coenzyme Q10 and Pluchea lanceolata against proton pump inhibitor-induced nephrotoxicity: Biochemical, histological, and ultrastructural evaluation. literature abstract metadata