Chinese Golden Larch
Pseudolarix amabilis
Pseudolarix amabilis, a tree native to East Asia, has not been traditionally used for medicinal purposes. Scientific research indicates potential biological activities; pseudolaric acid B induces ferroptosis in lung cancer cells and 17 diterpenoids from its seeds show cytotoxic activity against K562 cells, though the evidence is limited. Pseudolarolide B covalently targets PPP2R1A, enhancing PP2A holoenzyme assembly with anti-inflammatory effects, while (+)-catechin demonstrates significant antiparasitic activity against Dactylogyrus intermedius in goldfish. Safety concerns are currently minimal, and no major drug interactions have been recorded to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Pseudolaric acid B induces ferroptosis in lung cancer cells via JNK/ERK-mediated upregulation of survivin.
- The study identified 17 diterpenoids from Pseudolarix amabilis seeds and found that compounds 8 and 17 showed potential cytotoxic activity against K562 cells.
- (+)-Catechin from Pseudolarix amabilis showed antiparasitic activity against Dactylogyrus intermedius in goldfish with high efficacy and low toxicity.
- The study isolated several compounds from Pseudolarix amabilis seeds but found them not to have potent anti-inflammatory activities.
- Pseudolarolide B covalently targets PPP2R1A, enhancing PP2A holoenzyme assembly and exerting anti-inflammatory effects.
Frequently asked questions
What is Chinese Golden Larch?
Chinese Golden Larch (Pseudolarix amabilis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese Golden Larch?
5 sourced findings are recorded for Chinese Golden Larch; the strongest carries evidence grade D. For example: Pseudolaric acid B induces ferroptosis in lung cancer cells via JNK/ERK-mediated upregulation of survivin.
How strong is the evidence for Chinese Golden Larch?
The strongest finding for Chinese Golden Larch carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese Golden Larch safe? What are the side effects?
No major safety issues are recorded for Chinese Golden Larch in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese Golden Larch interact with medications?
No drug interactions are recorded for Chinese Golden Larch in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese Golden Larch?
Chinese Golden Larch is also known as: Лжелиственница, Mélèze de Chine.
Is Chinese Golden Larch a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 [Diterpenoid constituents in Pseudolarix amabilis and their antitumor activities in vitro]. literature abstract metadata
- T2 Pseudoamaolide P, a 1,2:3,4:9,10:9,19-tetraseco-cycloartane triterpene spiroketal lactone from seeds of Pseudolarix amabilis. literature abstract metadata
- T2 Antiparasitic effect of (+)-catechin derived from Pseudolarix amabilis against Dactylogyrus intermedius in goldfish. literature abstract metadata
- T2 Pseudolaric acid B promotes lung cancer cells ferroptosis depending on JNK/ERK-mediated upregulation of survivin. literature abstract metadata
- T2 Covalent targeting of PP2A scaffold subunit PPP2R1A by Pseudolarolide B enhances holoenzyme assembly to exert anti-inflammatory activity. literature abstract metadata