Guava

Psidium guajava

Psidium guajava, commonly known as the common or edible guava, originates from tropical regions of Central and South America but is now cultivated worldwide. Traditionally, its use has not been extensively documented in specific medical practices. However, scientific investigations have shown promising results. A study found that Psidium guajava ethanol extract was non-toxic up to 2000 mg/kg body weight in mice, indicating a potentially safe profile. Another study suggested that the fruit suspension might help reduce orthodontic tooth movement relapse in rats; yet, more research is needed to confirm these findings. Additionally, anodization of titanium plates using Psidium guava aqueous leaf extract showed no cytotoxicity and enhanced cell proliferation and adhesion compared to conventional methods. Notably, the study also identified seventeen glycerol-derived triazoles from the plant that exhibited varying levels of fungicidal activity against Neocosmospora falciformis, with some derivatives comparable to tebuconazole, a commercial fungicide. No major safety issues or drug interactions have been recorded for Psidium guava thus far.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found that Psidium guajava ethanol extract showed no acute or subacute toxicity up to 2000 mg/kg body weight in mice. D PMID
  • Psidium guajava fruit suspension showed a trend of reducing orthodontic relapse compared to control in Wistar rats, though further studies are needed. D PMID
  • The study found that using Psidium guajava aqueous leaf extract as an anodization electrolyte for titanium plates showed no cytotoxicity and enhanced cell proliferation and adhesion compared to conventional methods. D PMID
  • PGP reduced hyperuricemia markers and inflammation, modulated gut bacteria, and alleviated organ damage in mice. D PMID
  • Seventeen glycerol-derived triazoles showed varying degrees of fungicidal activity against Neocosmospora falciformis, with some derivatives comparable to the commercial fungicide tebuconazole. D PMID

Frequently asked questions

What is Guava?

Guava (Psidium guajava) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Guava?

5 sourced findings are recorded for Guava; the strongest carries evidence grade D. For example: The study found that Psidium guajava ethanol extract showed no acute or subacute toxicity up to 2000 mg/kg body weight in mice.

How strong is the evidence for Guava?

The strongest finding for Guava carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Guava safe? What are the side effects?

No major safety issues are recorded for Guava in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Guava interact with medications?

No drug interactions are recorded for Guava in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Guava?

Guava is also known as: Гуайява, goyavier.

Is Guava a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Study on the Alleviating Effect of Tropical Psidium guajava Basal Postbiotics on Hyperuricemia. literature abstract metadata
  2. T2 Fungicidal Activity and In Silico Studies of Triazoles Derived From Glycerol Against Neocosmospora falciformis, A Causal Agent of Guava Tree Decline. literature abstract metadata
  3. T2 In Vitro Biological Evaluation of Titanium Implants Anodized With Aqueous Extract of Psidium guajava and Conventional Electrolytes. literature abstract metadata
  4. T2 Use of Psidium guajava fruit suspension may prevent treatment relapse following orthodontic tooth movement in Wistar rat model. literature abstract metadata
  5. T2 Acute and sub-acute toxicological studies on the ethanol leaf extract of Psidium guajava in experimental mice. literature abstract metadata