Pulmonaria obscura
Pulmonaria obscura
Pulmonaria obscura, a member of the Boraginaceae family, is traditionally not used in any known medical practices. Scientific studies have identified six active compounds in shoot extracts and four in root extracts from 17 species, including P. obscura, highlighting its potential medicinal properties. While both Pulmonaria obscura roots and rhizomes contain pyrrolizidine alkaloids, leaves and inflorescences show trace amounts. The extracts demonstrated partial mitigation of peroxynitrite-induced oxidative stress in blood plasma and COX-2 inhibitory activity; however, the effects varied between P. obscura and its close relative P. officinalis. Yunnaneic acid B from both species effectively reduces peroxynitrite-induced oxidative stress without causing cytotoxicity, indicating potential antioxidant properties. No major safety issues or drug interactions have been recorded for Pulmonaria obscura to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified six active compounds in shoot extracts and four in root extracts of 17 Boraginaceae species, including Pulmonaria obscura.
- Pulmonaria obscura roots and rhizomes contain detectable levels of pyrrolizidine alkaloids, while leaves and inflorescences have trace amounts.
- The extracts from both Pulmonaria obscura and P. officinalis partially mitigated peroxynitrite-induced oxidative stress in blood plasma and showed COX-2 inhibitory activity, though effects varied between the species.
- Yunnaneic acid B from Pulmonaria officinalis L. effectively reduces peroxynitrite-induced oxidative stress in vitro without cytotoxicity.
Frequently asked questions
What is Pulmonaria obscura?
Pulmonaria obscura (Pulmonaria obscura) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pulmonaria obscura?
4 sourced findings are recorded for Pulmonaria obscura; the strongest carries evidence grade D. For example: The study identified six active compounds in shoot extracts and four in root extracts of 17 Boraginaceae species, including Pulmonaria obscura.
How strong is the evidence for Pulmonaria obscura?
The strongest finding for Pulmonaria obscura carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pulmonaria obscura safe? What are the side effects?
No major safety issues are recorded for Pulmonaria obscura in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pulmonaria obscura interact with medications?
No drug interactions are recorded for Pulmonaria obscura in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Pulmonaria obscura?
Pulmonaria obscura is also known as: Медуница неясная, Herbe-de-cœur.
Is Pulmonaria obscura a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Pyrrolizidine alkaloids in Pulmonaria obscura. literature abstract metadata
- T2 Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family. literature abstract metadata
- T2 Yunnaneic Acid B, a Component of Pulmonaria officinalis Extract, Prevents Peroxynitrite-Induced Oxidative Stress in Vitro. literature abstract metadata
- T2 Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors-In Vitro and In Silico Studies. literature abstract metadata