FolkKB

Chinese Pyrola

Pyrola calliantha

Pyrola calliantha, a plant native to mountainous regions in Asia and North America, has not been traditionally used for any specific medicinal purposes. Scientific investigations have identified various compounds within Pyrola calliantha and isolated bacteria such as Chryseobacterium pyrolae sp. nov. from its rhizosphere soil, hinting at potential biological activities but requiring further research to establish a clear connection between the plant's chemical constituents and their pharmacological effects. A study involving GBZTF, which is derived from Pyrola calliantha, showed alleviation of knee osteoarthritis symptoms in rats through modulating the Piezo1-Ca2+/PI3K-AKT/NF-κB axis, indicating possible anti-inflammatory properties; however, more comprehensive research is needed to confirm these findings. No significant safety concerns or known drug interactions have been recorded for Pyrola calliantha thus far.

At a glance
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • A novel bacterium, Chryseobacterium pyrolae sp. nov., was isolated from Pyrola calliantha rhizosphere soil. D PMID
  • A non-motile, Gram-negative bacterium named Chryseobacterium herbae was isolated from the rhizospheric soil of Pyrola calliantha. D PMID
  • GBZTF alleviates knee osteoarthritis symptoms and reduces inflammation in rats through modulating the Piezo1-Ca2+/PI3K-AKT/NF-κB axis. D PMID
  • The study found that Pyrola calliantha has various identified compounds and pharmacological activities, but more research is needed on its chemical constituents' relationship with pharmacodynamics. D PMID

Frequently asked questions

What is Chinese Pyrola?

Chinese Pyrola (Pyrola calliantha) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Chinese Pyrola?

4 sourced findings are recorded for Chinese Pyrola; the strongest carries evidence grade D. For example: A novel bacterium, Chryseobacterium pyrolae sp. nov., was isolated from Pyrola calliantha rhizosphere soil.

How strong is the evidence for Chinese Pyrola?

The strongest finding for Chinese Pyrola carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Chinese Pyrola safe? What are the side effects?

No major safety issues are recorded for Chinese Pyrola in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Chinese Pyrola interact with medications?

No drug interactions are recorded for Chinese Pyrola in our sources. This does not rule them out — check with a pharmacist.

Is Chinese Pyrola a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Pyrolae herba: A review on its botany, traditional uses, phytochemistry, pharmacology and quality control. literature abstract metadata
  2. T2 Chryseobacterium herbae Isolated from the Rhizospheric Soil of Pyrola calliantha H. Andres in Segrila Mountain on the Tibetan Plateau. literature abstract metadata
  3. T2 Chryseobacterium pyrolae sp. nov., isolated from the rhizosphere soil of Pyrola calliantha H. literature abstract metadata
  4. T2 Gubi Zhitong formula alleviates knee osteoarthritis induced by excessive mechanical loading in rats via regulating Piezo1 mediated Ca2+ signaling pathway and phosphoinositide 3-Kinase / protein kinase B / nuclear factor kappa-B axis. literature abstract metadata

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