Be Still Tree
Rauvolfia tetraphylla
Rauvolfia tetraphylla, a plant native to tropical regions of Africa, has not been traditionally used for medicinal purposes. Scientific studies have identified and characterized enzymes involved in the biosynthesis of monoterpenoid indole alkaloids from this plant, contributing to its potential biological activities. Research indicates that compounds derived from Rauvolfia tetraphylla may exhibit antiviral activity against SARS-CoV-2 and show promise as anti-proliferative agents in triple-negative breast cancer cells. Additionally, these compounds demonstrated inhibitory effects on the proliferation and migration of breast cancer cells both in vitro and in vivo, reducing tumor growth. No major safety concerns or known drug interactions have been recorded for Rauvolfia tetraphylla to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identifies and characterizes enzymes responsible for C3 stereochemistry inversion in Rauvolfia tetraphylla, contributing to the biosynthesis of monoterpenoid indole alkaloids.
- The study identified three compounds from Rauvolfia tetraphylla with potential antiviral activity against SARS-CoV-2.
- Rauvolfia tetraphylla extract and its isolated compounds showed potential anti-proliferative and apoptotic effects in triple-negative breast cancer cells.
- The study found that Rauvolfia tetraphylla-derived compounds inhibited breast cancer cell proliferation and migration in vitro and reduced tumor growth in vivo.
Frequently asked questions
What is Be Still Tree?
Be Still Tree (Rauvolfia tetraphylla) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Be Still Tree?
4 sourced findings are recorded for Be Still Tree; the strongest carries evidence grade D. For example: The study identifies and characterizes enzymes responsible for C3 stereochemistry inversion in Rauvolfia tetraphylla, contributing to the biosynthesis of monoterpenoid indole alkaloids.
How strong is the evidence for Be Still Tree?
The strongest finding for Be Still Tree carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Be Still Tree safe? What are the side effects?
No major safety issues are recorded for Be Still Tree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Be Still Tree interact with medications?
No drug interactions are recorded for Be Still Tree in our sources. This does not rule them out — check with a pharmacist.
Is Be Still Tree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Regulation of hippo signaling mediated apoptosis by Rauvolfia tetraphylla in triple-negative breast cancer. literature abstract metadata
- T2 Exploring Bioactive Compounds of Rauvolfia tetraphylla L. (RT) for 3CLprotease of SARS-CoV2: GC-MS Analysis and In-Silico Studies. literature abstract metadata
- T2 Targeting Yes-Associated Protein (YAP) in Breast Cancer: In Silico Molecular Dynamics, Luminescence-Based In Vitro, and In Vivo Validation of Rauvolfia tetraphylla-Derived Inhibitors. literature abstract metadata
- T2 Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion. literature abstract metadata