Heart-leaf Indian madder
Rubia cordifolia
Rubia cordifolia, also known as madder or Indian madder, is a traditional plant used in Ayurvedic and Unani medicine. Its traditional uses are not well-documented, but it has been employed for various purposes such as dyeing fabrics and treating skin conditions. Scientific evidence suggests that Rubia cordifolia possesses antioxidant, antimicrobial, and hepatoprotective properties. Studies indicate its potential benefits in modulating intestinal permeability and alleviating symptoms of ulcerative colitis through modulation of specific biological pathways; however, the clinical relevance remains uncertain due to variability in phytochemical composition among different plant sources. No significant safety concerns or known drug interactions have been reported for Rubia cordifolia.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study highlights Rubia cordifolia's diverse traditional uses and modern pharmacological properties including antioxidants, antimicrobials, and hepatoprotectants.
- This review highlights diverse pharmacological activities from Rubia plants but questions their clinical interchangeability due to varying phytochemical compositions.
- RBA significantly inhibited LPS- and TNF-α-induced increases in intestinal permeability and affected tight junction protein localization in Caco-2 cells.
- Self-assembled nanoparticles from carbonized Rubia cordifolia exhibit enhanced stability and alleviate UC by modulating the IL-17A/IL-22-C/EBPβ-STAT3 axis.
Frequently asked questions
What is Heart-leaf Indian madder?
Heart-leaf Indian madder (Rubia cordifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Heart-leaf Indian madder?
4 sourced findings are recorded for Heart-leaf Indian madder; the strongest carries evidence grade D. For example: The study highlights Rubia cordifolia's diverse traditional uses and modern pharmacological properties including antioxidants, antimicrobials, and hepatoprotectants.
How strong is the evidence for Heart-leaf Indian madder?
The strongest finding for Heart-leaf Indian madder carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Heart-leaf Indian madder safe? What are the side effects?
No major safety issues are recorded for Heart-leaf Indian madder in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Heart-leaf Indian madder interact with medications?
No drug interactions are recorded for Heart-leaf Indian madder in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Heart-leaf Indian madder?
Heart-leaf Indian madder is also known as: Марена сердцелистная, garance indien.
Is Heart-leaf Indian madder a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Therapeutic Potential of Ruberythric Acid in Intestinal Inflammation and Barrier Function Reduction. literature abstract metadata
- T2 Unveiling the Modern Therapeutic Properties and Folk Medicinal Riches of Rubia cordifolia. literature abstract metadata
- T2 A comprehensive review of Rubia medicinal plants: Traditional uses, botany, phytochemistry, and pharmacological activities. literature abstract metadata
- T2 Discovery of self-assembled nanoparticles from Rubia cordifolia L. before and after carbonization and mechanistic study on their targeted therapy for ulcerative colitis. literature abstract metadata