Hawthorn-leaved Bramble

Rubus crataegifolius

Rubus crataegifolius, also known as the thimbleberry, is a plant native to North America. While it has not been traditionally used in any specific medical practices or remedies, studies have shown promising results. In mice infected with CagA+ Helicobacter pylori, extracts from Rubus crataegifolius reduced bacterial levels and suppressed both acute and chronic inflammation. Additionally, four polysaccharides extracted from the roots demonstrated antioxidant activities and in vitro protective effects against H2O2-induced damage in HepG2 cells. The herbal complex also improved serum lipid profiles and reduced body weight and fat accumulation in mice fed a high-fat diet. In combination with Ulmus macrocarpa extracts, there was a synergistic effect against H. pylori, though individual minimum inhibitory concentrations were higher when used alone. No major safety issues or drug interactions have been recorded for Rubus crataegifolius, but further research is needed to confirm these findings in human studies.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • RUG-com reduced bacterial levels and suppressed both acute and chronic inflammation in mice infected with CagA+ Helicobacter pylori. D PMID
  • The study found that polysaccharides from Rubus crataegifolius roots, purified through column chromatography, showed antioxidant activity and reduced H2O2-induced oxidative damage in HepG2 cells. D PMID
  • The herbal complex treated mice showed reduced body weight, fat accumulation, and improved serum lipid profiles compared to the high-fat diet control group. D PMID
  • The study found that Rubus crataegifolius and Ulmus macrocarpa extracts showed a synergistic effect against H. pylori in vitro and in a mouse model. D PMID

Frequently asked questions

What is Hawthorn-leaved Bramble?

Hawthorn-leaved Bramble (Rubus crataegifolius) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Hawthorn-leaved Bramble?

4 sourced findings are recorded for Hawthorn-leaved Bramble; the strongest carries evidence grade D. For example: RUG-com reduced bacterial levels and suppressed both acute and chronic inflammation in mice infected with CagA+ Helicobacter pylori.

How strong is the evidence for Hawthorn-leaved Bramble?

The strongest finding for Hawthorn-leaved Bramble carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Hawthorn-leaved Bramble safe? What are the side effects?

No major safety issues are recorded for Hawthorn-leaved Bramble in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Hawthorn-leaved Bramble interact with medications?

No drug interactions are recorded for Hawthorn-leaved Bramble in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Hawthorn-leaved Bramble?

Hawthorn-leaved Bramble is also known as: Малина боярышниколистная.

Is Hawthorn-leaved Bramble a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Standardized Combined Plant Extract, RUG-com, Reduces Bacterial Levels and Suppresses Acute and Chronic Inflammation in Balb/c Mice Infected with CagA+ Helicobacter pylori. literature abstract metadata
  2. T2 Synergistic Effect of Rubus crataegifolius and Ulmus macrocarpa Against Helicobacter pylori Clinical Isolates and Gastritis. literature abstract metadata
  3. T2 Protective Effects of Polyphenol Enriched Complex Plants Extract on Metabolic Dysfunctions Associated with Obesity and Related Nonalcoholic Fatty Liver Diseases in High Fat Diet-Induced C57BL/6 Mice. literature abstract metadata
  4. T2 Optimization of enzyme-assisted microwave extraction, structural characterization, antioxidant activity and in vitro protective effect against H2O2-induced damage in HepG2 cells of polysaccharides from roots of Rubus crataegifolius Bunge. literature abstract metadata