sage
Salvia officinalis
Salvia officinalis, commonly known as sage, is a traditional plant with origins in the Mediterranean region. Traditionally, its use has not been extensively documented; however, it has been employed in various cultural practices for culinary and potential medicinal purposes. Scientific evidence suggests that extracts of Salvia officinalis can influence drug metabolism by increasing mRNA levels of drug-metabolizing enzymes by 2-8 fold, though the strength of this evidence is moderate. In a study involving rabbits, sage essential oil demonstrated significant amelioration of liver damage and oxidative stress following exposure to Lambda-cyhalothrin. Additionally, Salvia officinalis waste has shown high removal efficiencies (up to 99%) for textile dyes with biosorption capacities fitting Freundlich and Langmuir models. Shading with blue nets generally increased yield and improved the quality of sage essential oils, particularly in the first two harvests, while unshaded plants yielded more in the third harvest. No major safety issues or recorded drug interactions have been identified for Salvia officinalis.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- All three herbs increased mRNA levels of drug-metabolizing enzymes by 2-8 fold.
- Salvia officinalis waste showed high removal efficiencies (up to 99%) for textile dyes with biosorption capacities fitting Freundlich and Langmuir models.
- Salvia officinalis essential oil showed significant amelioration of liver damage and oxidative stress in rabbits exposed to Lambda-cyhalothrin.
- Shading with blue nets generally increased yield and improved quality of sage essential oils, particularly in the first two harvests, while unshaded plants yielded more in the third harvest.
- Salvia officinalis was among the plants documented for respiratory conditions, with uses converging partly with contemporary pharmacology.
- Sage extract showed high α-amylase inhibitory activity (79.60%) among tested plants.
- Salvia officinalis, Pistacia vera, and Eucalyptus sp. extracts showed varying levels of insecticidal activity against Phlebotomus papatasi, with S. officinalis exhibiting the highest efficacy.
- Salvia officinalis extracts were among those used to biosynthesize CuO-ZnO nanoparticles integrated into nanocomplexes showing antimicrobial and protein delivery potential.
Frequently asked questions
What is sage?
sage (Salvia officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about sage?
8 sourced findings are recorded for sage; the strongest carries evidence grade D. For example: All three herbs increased mRNA levels of drug-metabolizing enzymes by 2-8 fold.
How strong is the evidence for sage?
The strongest finding for sage carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is sage safe? What are the side effects?
No major safety issues are recorded for sage in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does sage interact with medications?
No drug interactions are recorded for sage in our sources. This does not rule them out — check with a pharmacist.
What are the common names of sage?
sage is also known as: шалфей, Sauge officinale.
Is sage a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Sustainable waste assessment using waste biomasses in the removal of toxic textile dyes. literature abstract metadata
- T2 Insecticidal Activity of Salvia officinalis, Pistacia vera and Eucalyptus sp. Extracts Against Phlebotomus papatasi: A Potential Plant-Based Approach for Vector Control. literature abstract metadata
- T2 Exploring the Protective Potential of Salvia officinalis Essential Oil Against Lambda-Cyhalothrin-Induced Liver Injury and Oxidative Stress in Male Rabbits: Biochemical and Histopathological Assessment. literature abstract metadata
- T2 Transcript-Level Modulation of Drug-Metabolizing Enzymes by Echinacea, Salvia, and Thymus in Adult Male Rats: Implications for Herb-Drug Interactions. literature abstract metadata
- T2 Polymer-stabilized amorphous CuO-ZnO hybrid nanocomplex as a promising candidate for antimicrobial therapy and controlled drug delivery with molecular docking insights. literature abstract metadata
- T2 Ethnopharmacobotanical investigation of plants used for respiratory disorders in Transylvania, Romania. literature abstract metadata
- T2 Natural α-Amylase Inhibitors from Medicinal Herbs: In Vitro Evaluation of Extracts Prepared with Food-Compatible Solvents. literature abstract metadata
- T2 Influence of Shading on Essential Oil Quantity and Quality of Sage (Salvia officinalis L.) at Different Harvest Times. literature abstract metadata