Siebold’s greenbrier
Smilax sieboldii
Smilax sieboldii is a plant traditionally found in East Asia. While its specific traditional medicinal uses are not well-documented, it has been studied for its phylogeographic structure and chemical composition. Research indicates that different seas have acted as barriers or corridors during historical sea-level fluctuations, influencing the population divergence of Smilax sieboldii in East Asia. Additionally, over 40 unique steroidal saponins have been identified in this plant using advanced analytical techniques, suggesting potential medicinal properties. Some studies show varying degrees of inhibition on fat accumulation in adipocytes, though the evidence is not yet strong enough to support specific therapeutic applications. Notably, seven out of twelve supplements containing Smilax sieboldii were found to contain spirostane-type contaminants, including unlabeled steroids, which may indicate a lack of quality control measures. No major safety issues or drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The phylogeographic structure of Smilax sieboldii showed that different seas acted as barriers or corridors during historical sea-level fluctuations, influencing population divergence in East Asia.
- More than 40 unique steroidal saponins were identified in Smilax sieboldii using UHPLC-QToF-MS/MS and molecular networking.
- Compounds isolated from Smilax sieboldii showed varying degrees of inhibition on fat accumulation in 3T3-L1 adipocytes.
- Seven out of twelve supplements contained spirostane-type contaminants, including unlabeled steroids, indicating potential lack of quality controls.
Frequently asked questions
What is Siebold’s greenbrier?
Siebold’s greenbrier (Smilax sieboldii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Siebold’s greenbrier?
4 sourced findings are recorded for Siebold’s greenbrier; the strongest carries evidence grade D. For example: The phylogeographic structure of Smilax sieboldii showed that different seas acted as barriers or corridors during historical sea-level fluctuations, influencing population divergence in East Asia.
How strong is the evidence for Siebold’s greenbrier?
The strongest finding for Siebold’s greenbrier carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Siebold’s greenbrier safe? What are the side effects?
No major safety issues are recorded for Siebold’s greenbrier in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Siebold’s greenbrier interact with medications?
No drug interactions are recorded for Siebold’s greenbrier in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Siebold’s greenbrier?
Siebold’s greenbrier is also known as: Сассапариль Зибольда.
Is Siebold’s greenbrier a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 The power of hyphenated chromatography-Time of flight mass spectrometry for unequivocal identification of spirostanes in bodybuilding dietary supplements. literature abstract metadata
- T2 Anti-Adipogenic Activity of Secondary Metabolites Isolated from Smilax sieboldii Miq. on 3T3-L1 Adipocytes. literature abstract metadata
- T2 6-Oxofurostane and (iso)Spirostane Types of Saponins in Smilax sieboldii: UHPLC-QToF-MS/MS and GNPS-Molecular Networking Approach for the Rapid Dereplication and Biodistribution of Specialized Metabolites. literature abstract metadata
- T2 Contrasting Roles of the Multiple Seas in East Asia on Population Divergence of Smilax sieboldii (Smilacaceae). literature abstract metadata