Simple-stem Bur-reed

Sparganium stoloniferum

Sparganium stoloniferum, a plant traditionally not associated with any specific medicinal use in known traditions, has been studied for its potential benefits. Scientific evidence suggests that it may play a role in inhibiting endometriosis progression through modulation of sphingolipid metabolism via the S1P/S1PR1-Akt axis, particularly when harvested in winter, which shows increased density and starch accumulation associated with tissue maturation. Additionally, simulated warming conditions have been observed to decrease biomass accumulation in both Zizania caduciflor and Sparganium stoloniferum. β-elemene from Curcuma phaeocaulis has shown potential for inhibiting endometriosis development through ferroptosis via MAPK and STAT3 signaling pathways, but there is no direct evidence linking these effects to Sparganium stoloniferum itself. No major safety concerns or recorded drug interactions have been noted for this plant.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found that Sanleng Wan inhibited endometriosis progression in rats by modulating sphingolipid metabolism via the S1P/S1PR1-Akt axis. D PMID
  • β-Elemene from Curcuma phaeocaulis inhibits endometriosis development in vitro and in mice by inducing ferroptosis via MAPK and STAT3 pathways. D PMID
  • Winter-harvest Sparganium stoloniferum tubers show increased density, cell-wall thickening, and starch accumulation, associated with coordinated tissue consolidation and transcriptional changes. D PMID
  • Simulated warming significantly decreased the biomass accumulation of both Zizania caduciflor and Sparganium stoloniferum. D PMID

Frequently asked questions

What is Simple-stem Bur-reed?

Simple-stem Bur-reed (Sparganium stoloniferum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Simple-stem Bur-reed?

4 sourced findings are recorded for Simple-stem Bur-reed; the strongest carries evidence grade D. For example: The study found that Sanleng Wan inhibited endometriosis progression in rats by modulating sphingolipid metabolism via the S1P/S1PR1-Akt axis.

How strong is the evidence for Simple-stem Bur-reed?

The strongest finding for Simple-stem Bur-reed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Simple-stem Bur-reed safe? What are the side effects?

No major safety issues are recorded for Simple-stem Bur-reed in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Simple-stem Bur-reed interact with medications?

No drug interactions are recorded for Simple-stem Bur-reed in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Simple-stem Bur-reed?

Simple-stem Bur-reed is also known as: Ежеголовник побегоносный.

Is Simple-stem Bur-reed a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 β-elemene, a sesquiterpene constituent from Curcuma phaeocaulis inhibits the development of endometriosis by inducing ferroptosis via the MAPK and STAT3 signaling pathways. literature abstract metadata
  2. T2 Simulated Warming Reduces Biomass Accumulation in Zizania caduciflor and Sparganium stoloniferum. literature abstract metadata
  3. T2 Sanleng Wan inhibits endometriosis progression by regulating sphingolipid metabolism via the S1P/S1PR1-Akt axis based on serum metabolomics and network pharmacology. literature abstract metadata
  4. T2 Coordinated Cell-Wall and Starch Maturation Is Associated with Winter-Harvest Quality in Sparganium stoloniferum Tubers. literature abstract metadata